View source for Metal fume fever

==Background==
*AKA brass founders' ague, brass shakes, zinc shakes, galvie flu, metal dust fever, Welding Shivers, Monday morning fever
*Syndrome caused by inhalation of certain metals (most commonly zinc, copper, cadmium, but also aluminum, lead, nickel and various other metals<ref>https://www.twi-global.com/technical-knowledge/faqs/faq-what-is-metal-fume-fever</ref>) in form of dust or fumes, usually through hot metalworking such as welding, brazing, smelting, or soldering. 
*Thought to be due to metals stimulating cytokine release

==Clinical Features==
*[[Flu-like illness]]; [[fever]], [[fatigue]]/malaise, [[myalgia]], [[arthralgia]], [[myalgia]], [[headache]]
**Usually resolves in 24-48h
*+/- [[SOB]], [[chest pain]], [[pneumonitis]]
**Rarely, severe lung injury, [[ARDS]] picture
*+/- [[hypotension]], [[AMS|LOC]], [[seizure]], [[AKI]] in severe cases

==Differential Diagnosis==
{{ILI DDX}}


==Evaluation==
*Clinical diagnosis, evaluate for alternate diagnoses
*[[CXR]] and CT chest often unremarkable in milder cases but may show ground-glass opacities or other findings<ref>Kunimasa, Kei; Arita, Machiko; Tachibana, Hiromasa; Tsubouchi, Kazuya; Konishi, Satoshi; Korogi, Yohei; Nishiyama, Akihiro; Ishida, Tadashi (2011). "Chemical Pneumonitis and Acute Lung Injury Caused by Inhalation of Nickel Fumes". Internal Medicine. 50 (18): 2035–8.</ref>
*CBC- may have [[leukocytosis]] with neutrophil predominance<ref>Kaye P, Young H, O'sullivan I. Metal fume fever: a case report and review of the literature. Emerg Med J. 2002;19(3):268-9.</ref>

==Management==
*Supportive
*Most cases self-limiting within 24-48h

==Disposition==
*Discharge if clinically stable

==See Also==


==External Links==


==References==
<references/>
[[Category:Toxicology]] [[Category:Pulmonary]]