View source for Metabolic dysfunction-associated steatohepatitis (MASH)

==Background==
*Formerly known as [[non alcoholic steatohepatitis]]
[[File:Stage of liver damage high.jpg|thumb|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
[[File:Sobo 1906 389.png|thumb|Inferior view of the liver with surface showing lobes and impressions.]]
[[File:Liver vascular anatomy.png|thumb|Liver vascular anatomy.]]
[[File:Biliary system multilingual.png|thumb|Bile duct and pancreas anatomy. 1. Bile ducts: 2. Intrahepatic bile ducts; 3. Left and right hepatic ducts; 4. Common hepatic duct; 5. Cystic duct; 6. Common bile duct; 7. Sphincter of Oddi; 8. Major duodenal papilla; 9. Gallbladder; 10-11. Right and left lobes of liver; 12. Spleen; 13. Esophagus; 14. Stomach; 15. Pancreas: 16. Accessory pancreatic duct; 17. Pancreatic duct; 18. Small intestine; 19. Duodenum; 20. Jejunum; 21-22: Right and left kidneys.]]
*Fatty liver disease due to causes other than excessive alcohol
*Associated with insulin resistance and [[metabolic syndrome]]

==Clinical Features==
*Often asymptomatic or with mild [[RUQ pain|RUQ discomfort]]
*Signs of portal hypertension (e.g. [[ascites]]) if advanced fibrosis
*[[Hepatomegaly]]

==Differential Diagnosis==
{{Hepatomegaly DDX}}

==Evaluation==
*[[LFTs]], CBC
*[[RUQ US]]
*Outpatient elastography/Fibroscan

==Management==
*Treat complications of portal hypertension, if present
*Counsel on weight loss, increased coffee consumption
*Vitamin E if known F2 fibrosis

==Disposition==
*Discharge unless complications

==See Also==
*[[Hepatomegaly]]

==External Links==

==References==
<references/>

[[Category:GI]]