View source for Captopril

==Administration==
*Type: [[ACE inhibitor]]
*Dosage Forms:
*Routes of Administration: Oral
*Common Trade Names:

==Adult Dosing==
*6.25-150mg PO three times per day
==Pediatric Dosing==
''Safety/efficacy not established in pediatric patients''
==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: D
*[[Lactation risk categories|Lactation risk]]: Infant risk minimal
*Renal dosing: Initial dose should be reduced, titrate in smaller increments

==Contraindications==
*Allergy to class/drug
*History of ACE-inhibitor induced angioedema

==Adverse Reactions==
===Serious===
*Angioedema
*Stevens-Johnson syndrome
*Agranulocytosis, neutropenia
===Common===
*Hypotension
*Hyperkalemia
*Cough
*Rash
==Pharmacology==
*Half-life: < 3 hours
*Metabolism: 
*Excretion: Renal, dialzable

==Mechanism of Action==
*Inhibits angiotensin I-converting enzyme, blocks conversion of angiotensin I--> angiotensin II
==Comments==

==See Also==
*[[ACE-inhibitors]]
==References==
<references/>
[[Category:Pharmacology]]