Codeine - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:55:54Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:55, 20 March 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:25:16Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

← Older revision		Revision as of 17:25, 20 March 2026
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	\|format=broadtable		\|format=broadtable
	\|headers=plain		\|headers=plain
	\|~~link~~=~~subject~~		\|mainlabel=-
	\|sort=Has Indication		\|sort=Has Indication
	\|limit=50		\|limit=50

Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:43:25Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

@@ Line 59: / Line 59: @@
 ==Mechanism of Action==
 *Opioid agonist
 ==See Also==

ClaireLewis: /* Administration */

2019-09-20T17:47:33Z

Administration

← Older revision		Revision as of 17:47, 20 September 2019
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	==Administration==		==Administration==
	*Type: Opioid		*Type: [[Opioid]] analgesic, antitussive
	*Dosage Forms: Tablet: 15, 30, 60 Oral Solution: 30mg/5 mL		*Dosage Forms: Tablet: 15, 30, 60 Oral Solution: 30mg/5 mL
	*Routes of Administration: Oral		*Routes of Administration: Oral
	*Pharmacologic Category: Analgesic, Opioid; Antitussive

	==Blackbox Warning==		==Blackbox Warning==

Fletc151: /* References */

2019-06-13T14:28:22Z

References

← Older revision		Revision as of 14:28, 13 June 2019
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	==References==		==References==
	*Micromedex		*Micromedex
	*~~UptoDate~~		*Ahlfors CE. Benzyl alcohol, kernicterus, and unbound bilirubin. J Pediatr. 2001;139(2):317-319. [PubMed 11487763]
			*American College of Obstetricians and Gynecologists (ACOG) Committee on Practice Bulletins—Obstetrics. Practice bulletin no. 177: obstetric analgesia and anesthesia. Obstet Gynecol. 2017 129(4):e73-e89. [PubMed 28333819]
			*American Pain Society. Principles of Analgesic. 7th ed, Glenview, IL: American Pain Society, 2016.
			*Aronoff GR, Bennett WM, Berns JS, et al, Drug Prescribing in Renal Failure: Dosing Guidelines for Adults and Children, 5th ed. Philadelphia, PA: American College of Physicians; 2007, p 18, 135.
			*Aurora RN, Kristo DA, Bista SR, et al. The treatment of restless legs syndrome and periodic limb movement disorder in adults—an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine clinical practice guideline. Sleep. 2012;35(8):1039-1062. [PubMed 22851801]
			*Berna C, Kulich RJ, Rathmell JP. Tapering long-term opioid therapy in chronic noncancer pain: evidence and recommendations for everyday practice. Mayo Clin Proc. 2015;90(6):828-842. doi: 10.1016/j.mayocp.2015.04.003. [PubMed 26046416]
			*Bolser DC, “Cough Suppressant and Pharmacologic Protussive Therapy: ACCP Evidence-Based Clinical Practice Guidelines,” Chest, 2006, 129(1 Suppl):238-48. [PubMed 16428717]
			*Brennan MJ. The effect of opioid therapy on endocrine function. Am J Med. 2013;126(3)(suppl 1):S12-S18. doi: 10.1016/j.amjmed.2012.12.001. [PubMed 23414717]
			*Broussard CS, Rasmussen SA, Reefhuis J, et al, "National Birth Defects Prevention Study: Maternal Treatment With Opioid Analgesics and Risk for Birth Defects," Am J Obstet Gynecol, 2011, 204(4):314. [PubMed 21345403]
			*Cardan E, “Fatal Case of Codeine Poisoning,” Lancet, 1981, 1(8233):1313.
			*Centers for Disease Control (CDC). Neonatal deaths associated with use of benzyl alcohol—United States. MMWR Morb Mortal Wkly Rep. 1982;31(22):290-291. http://www.cdc.gov/mmwr/preview/mmwrhtml/00001109.htm.

	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Mholtz: Text replacement - "prn" to "PRN"

2017-07-07T12:14:55Z

Text replacement - "prn" to "PRN"

← Older revision		Revision as of 12:14, 7 July 2017
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	==Adult Dosing==		==Adult Dosing==
	*Mild to moderate pain: 15-60mg PO q4-6h ~~prn~~		*Mild to moderate pain: 15-60mg PO q4-6h PRN
	**Max: 360mg/day		**Max: 360mg/day
	**Give with food		**Give with food
	**Doses >60mg are rarely more effective in opioid-naive patients		**Doses >60mg are rarely more effective in opioid-naive patients

	*Cough: 15-30mg PO q4-6h ~~prn~~		*Cough: 15-30mg PO q4-6h PRN
	**Max: 120mg/day		**Max: 120mg/day

	*[[Diarrhea]]: 45-270mg/day PO divided q4-6h ~~prn~~		*[[Diarrhea]]: 45-270mg/day PO divided q4-6h PRN
	**Start: 30-60mg/day PO divided QD-bid, then increase by 30-60mg/day ~~prn~~		**Start: 30-60mg/day PO divided QD-bid, then increase by 30-60mg/day PRN
	**Max: 60mg/dose up to 270mg/day		**Max: 60mg/dose up to 270mg/day

	==Pediatric Dosing==		==Pediatric Dosing==
	*Pain, mild-moderate		*Pain, mild-moderate
	**3-6 yo: 0.5-1mg/kg PO q4-6h ~~prn~~		**3-6 yo: 0.5-1mg/kg PO q4-6h PRN
	**7-12 yo: 15-30mg PO q4-6h ~~prn~~		**7-12 yo: 15-30mg PO q4-6h PRN
	**13-17 yo: 15-60mg PO q4-6h ~~prn~~		**13-17 yo: 15-60mg PO q4-6h PRN
	**Max: 60mg/dose up to 360mg/day		**Max: 60mg/dose up to 360mg/day
	*Cough		*Cough
	**2-5 yo: 1-1.5mg/kg/day PO divided q4-6h ~~prn~~; Max: 30mg/day		**2-5 yo: 1-1.5mg/kg/day PO divided q4-6h PRN; Max: 30mg/day
	**6-11 yo: 1-1.5mg/kg/day PO divided q4-6h ~~prn~~; Max: 60mg/day		**6-11 yo: 1-1.5mg/kg/day PO divided q4-6h PRN; Max: 60mg/day
	==Special Populations==		==Special Populations==
	*Pregnancy risk factor: C		*Pregnancy risk factor: C

Mholtz: Text replacement - "qd" to "QD"

2017-07-07T06:52:30Z

Text replacement - "qd" to "QD"

← Older revision		Revision as of 06:52, 7 July 2017
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	*[[Diarrhea]]: 45-270mg/day PO divided q4-6h prn		*[[Diarrhea]]: 45-270mg/day PO divided q4-6h prn
	**Start: 30-60mg/day PO divided qd-bid, then increase by 30-60mg/day prn		**Start: 30-60mg/day PO divided QD-bid, then increase by 30-60mg/day prn
	**Max: 60mg/dose up to 270mg/day		**Max: 60mg/dose up to 270mg/day

Rossdonaldson1: Text replacement - "Diarrhea" to "Diarrhea"

2016-09-24T18:05:23Z

Text replacement - "*Diarrhea" to "*Diarrhea"

← Older revision		Revision as of 18:05, 24 September 2016
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	**Max: 120mg/day		**Max: 120mg/day

	*Diarrhea: 45-270mg/day PO divided q4-6h prn		*[[Diarrhea]]: 45-270mg/day PO divided q4-6h prn
	**Start: 30-60mg/day PO divided qd-bid, then increase by 30-60mg/day prn		**Start: 30-60mg/day PO divided qd-bid, then increase by 30-60mg/day prn
	**Max: 60mg/dose up to 270mg/day		**Max: 60mg/dose up to 270mg/day

Neil.m.young: Text replacement - "1 mg" to "1mg"

2016-07-21T15:08:14Z

Text replacement - "1 mg" to "1mg"

← Older revision		Revision as of 15:08, 21 July 2016
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	==Pediatric Dosing==		==Pediatric Dosing==
	*Pain, mild-moderate		*Pain, mild-moderate
	**3-6 yo: 0.5-~~1 mg~~/kg PO q4-6h prn		**3-6 yo: 0.5-1mg/kg PO q4-6h prn
	**7-12 yo: 15-30mg PO q4-6h prn		**7-12 yo: 15-30mg PO q4-6h prn
	**13-17 yo: 15-60mg PO q4-6h prn		**13-17 yo: 15-60mg PO q4-6h prn

Neil.m.young: Text replacement - "5 mg" to "5mg"

2016-07-19T23:28:42Z

Text replacement - "5 mg" to "5mg"

← Older revision		Revision as of 23:28, 19 July 2016
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	**Max: 60mg/dose up to 360mg/day		**Max: 60mg/dose up to 360mg/day
	*Cough		*Cough
	**2-5 yo: 1-1.~~5 mg~~/kg/day PO divided q4-6h prn; Max: 30mg/day		**2-5 yo: 1-1.5mg/kg/day PO divided q4-6h prn; Max: 30mg/day
	**6-11 yo: 1-1.~~5 mg~~/kg/day PO divided q4-6h prn; Max: 60mg/day		**6-11 yo: 1-1.5mg/kg/day PO divided q4-6h prn; Max: 60mg/day
	==Special Populations==		==Special Populations==
	*Pregnancy risk factor: C		*Pregnancy risk factor: C