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Creatinine - Revision history
2026-04-16T18:56:01Z
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Danbot: Create lab page for Creatinine with EM-focused content and references
2026-03-22T06:58:09Z
<p>Create lab page for Creatinine with EM-focused content and references</p>
<p><b>New page</b></p><div>==Background==<br />
*Byproduct of muscle metabolism; freely filtered by the kidney<br />
*Primary marker of renal function in the ED<br />
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==Normal Values==<br />
*Normal: 0.6-1.2 mg/dL (varies by age, sex, muscle mass)<br />
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==Interpretation==<br />
*Elevated creatinine indicates decreased renal clearance; may lag 24-48 hours behind acute injury<br />
*A "normal" creatinine in elderly or low-muscle-mass patients may actually represent significant renal impairment<br />
*Acute rise of >0.3 mg/dL from baseline or 1.5x baseline defines [[acute kidney injury]] by KDIGO criteria<ref>Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012; 120(4):c179-184. PMID 22890468.</ref><br />
*Drugs that increase creatinine without true renal injury: trimethoprim, cimetidine, cobicistat<br />
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==See Also==<br />
*[[Acute kidney injury]]<br />
*[[BUN]]<br />
*[[GFR]]<br />
*[[BMP]]<br />
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==References==<br />
<references/><br />
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[[Category:Labs]]</div>
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