Herpes labialis - Revision history

Danbot: Strip excess bold

2026-03-22T09:33:00Z

Strip excess bold

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	===Classic Phases===		===Classic Phases===
	*~~'''~~Prodromal (day 0–1)~~'''~~: Tingling, itching, and reddening of the skin around the infected site		*Prodromal (day 0–1): Tingling, itching, and reddening of the skin around the infected site
	*~~'''~~Inflammation (day 1)~~'''~~: Swelling and redness		*Inflammation (day 1): Swelling and redness
	*~~'''~~Pre-sore (day 2–3)~~'''~~: Tiny, hard, inflamed papules and vesicles that may itch and are painfully sensitive to touch.		*Pre-sore (day 2–3): Tiny, hard, inflamed papules and vesicles that may itch and are painfully sensitive to touch.
	*~~'''~~Open lesion (day 4)~~'''~~: Vesicles break open and merge to create one big, open, weeping ulcer. May develop a fever and lymphadenopathy		*Open lesion (day 4): Vesicles break open and merge to create one big, open, weeping ulcer. May develop a fever and lymphadenopathy
	*~~'''~~Crusting (day 5–8)~~'''~~: A honey/golden crust starts to form from the syrupy exudate.		*Crusting (day 5–8): A honey/golden crust starts to form from the syrupy exudate.
	*~~'''~~Healing (day 9–14)~~'''~~: New skin begins to form underneath the scab. A series of scabs will form over the sore (called [[Meier Complex]]), each one smaller than the last. Irritation, itching, and some pain are common.		*Healing (day 9–14): New skin begins to form underneath the scab. A series of scabs will form over the sore (called [[Meier Complex]]), each one smaller than the last. Irritation, itching, and some pain are common.
	*~~'''~~Post-scab (12–14 days)~~'''~~: A reddish area may linger at the site of infection.		*Post-scab (12–14 days): A reddish area may linger at the site of infection.

	==Differential Diagnosis==		==Differential Diagnosis==

Rossdonaldson1: /* Background */

2026-01-07T00:34:16Z

Background

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	==Background==		==Background==
	*Cause of the common "cold sore"		*Cause of the common "cold sore"
	*Sores typically heal within 2–3 weeks, but the herpes virus remains dormant in the facial nerve branches, following orofacial infection, periodically reactivating (in symptomatic people) to create sores in the same area of the mouth or face at the site of the original infection.		*Sores typically heal within 2–3 weeks, but the herpes virus (typically HSV-1) remains dormant in the facial nerve branches, following orofacial infection, periodically reactivating (in symptomatic people) to create sores in the same area of the mouth or face at the site of the original infection.
	**Frequency varies from rare episodes to 12 or more recurrences per year (typically 1-3 attacks per year)		**Frequency varies from rare episodes to 12 or more recurrences per year (typically 1-3 attacks per year)
	**The frequency and severity of outbreaks generally decreases over time.		**The frequency and severity of outbreaks generally decreases over time.

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T21:17:10Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

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	{{DDX oral rashes and lesions}}		{{DDX oral rashes and lesions}}

	==~~Diagnosis~~==		==Evaluation==
	{{HSV-1 standard diagnosis}}		{{HSV-1 standard diagnosis}}

Rossdonaldson1: /* Disposition */

2016-04-26T21:24:56Z

Disposition

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	==Disposition==		==Disposition==
	*~~Outpatient~~		*Discharge if uncomplicated
			*Consider admission if immunocompromized, critically ill, or with large necrotic ulcers

	==See Also==		==See Also==

Rossdonaldson1: /* Differential Diagnosis */

2016-04-26T21:09:45Z

Differential Diagnosis

← Older revision		Revision as of 21:09, 26 April 2016
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	{{HSV-1 DDX}}		{{HSV-1 DDX}}

	{{DDX oral rashes and lesions]]		{{DDX oral rashes and lesions}}

	==Diagnosis==		==Diagnosis==

Rossdonaldson1: /* Differential Diagnosis */

2016-04-26T21:09:35Z

Differential Diagnosis

← Older revision		Revision as of 21:09, 26 April 2016
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	==Differential Diagnosis==		==Differential Diagnosis==
	{{HSV-1 DDX}}		{{HSV-1 DDX}}

			{{DDX oral rashes and lesions]]

	==Diagnosis==		==Diagnosis==

Rossdonaldson1: /* See Also */

2016-04-26T21:02:28Z

Rossdonaldson1: /* Background */

2016-04-26T21:00:08Z

Background

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	**Frequency varies from rare episodes to 12 or more recurrences per year (typically 1-3 attacks per year)		**Frequency varies from rare episodes to 12 or more recurrences per year (typically 1-3 attacks per year)
	**The frequency and severity of outbreaks generally decreases over time.		**The frequency and severity of outbreaks generally decreases over time.
			*Treatment does not affect dormant virus in nerve ganglions → recurrent disease remains possible

	==Clinical Features==		==Clinical Features==

Rossdonaldson1: /* See Also */

2016-04-25T21:40:50Z

Rossdonaldson1: /* Disposition */

2016-04-25T21:40:30Z

Disposition

← Older revision		Revision as of 21:40, 25 April 2016
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	==Disposition==		==Disposition==
			*Outpatient

	==See Also==		==See Also==

← Older revision		Revision as of 21:02, 26 April 2016
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	==See Also==		==See Also==
	*[[Herpes Simplex Virus-1]]		*[[Herpes Simplex Virus-1]]
			*[[Oropharynx and jaw diagnoses]]

	==External Links==		==External Links==