Hypermagnesemia - Revision history

Danbot: Add MedicationDose entries (furosemide, calcium chloride, calcium gluconate) with SMW annotations

2026-03-20T18:23:40Z

Add MedicationDose entries (furosemide, calcium chloride, calcium gluconate) with SMW annotations

@@ Line 40: / Line 40: @@
 *[[Calcium chloride]] 10% 5-10mL IV or [[calcium gluconate]] 10% 15-30mL IV  over 5min
 *Consider hemodialysis for Mg >8 or poor renal function
 ==Disposition==

2021-02-23T23:35:03Z

2021-02-11T22:17:21Z

2019-09-29T01:06:19Z

← Older revision		Revision as of 01:06, 29 September 2019
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	==Clinical Features==		==Clinical Features==
	*[[Nausea and vomiting]]		*[[Nausea and vomiting]]
	*Loss of reflexes and diaphragmatic paralysis (at very high levels)		*Loss of reflexes and [[respiratory failure\|diaphragmatic paralysis]] (at very high levels)

	{\| class="wikitable"		{\| class="wikitable"
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	*[[Renal Failure]]		*[[Renal Failure]]
	*[[Lithium]]		*[[Lithium]]
	*Volume depletion		*[[hypovolemia\|Volume depletion]]
	*[[Rhabdo]]		*[[Rhabdo]]
	*IV Mg (goal in PET/eclampsia 5-7 mEq/L)		*IV Mg (goal in PET/[[eclampsia]] 5-7 mEq/L)
	*Massive PO intake (laxative abusers, accidental Epsom salts)		*Massive PO intake ([[bulimia nervosa\|laxative abusers]], accidental Epsom salts)
	*Magnesium enemas<ref>Schelling Fatal hypermagnesemia. JR1. Clin Nephrol. 2000 Jan;53(1):61-5.</ref>		*Magnesium enemas<ref>Schelling Fatal hypermagnesemia. JR1. Clin Nephrol. 2000 Jan;53(1):61-5.</ref>

2017-05-22T06:40:36Z

Evaluation

2017-05-22T06:40:18Z

Management

← Older revision		Revision as of 06:40, 22 May 2017
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	*[[IVF]]		*[[IVF]]
	*[[Furosemide]] 20-40mg IV		*[[Furosemide]] 20-40mg IV
	*[[~~CaCl~~]] 10% 5-10mL IV or [[Ca gluconate]] 10% 15-30mL IV over 5min		*[[Calcium chloride]] 10% 5-10mL IV or [[calcium gluconate]] 10% 15-30mL IV over 5min
	*Consider hemodialysis for Mg >8 or poor renal function		*Consider hemodialysis for Mg >8 or poor renal function

2017-05-22T06:35:25Z

← Older revision		Revision as of 06:35, 22 May 2017
Line 5:		Line 5:

	==Clinical Features==		==Clinical Features==
	*Nausea and vomiting		*[[Nausea and vomiting]]
	*Loss of reflexes and diaphragmatic paralysis (at very high levels)		*Loss of reflexes and diaphragmatic paralysis (at very high levels)

	~~==Differential Diagnosis==~~
	*[[Renal Failure]]
	*[[Lithium]]
	*Volume depletion
	*[[Rhabdo]]
	*IV Mg (goal in PET/eclampsia 5-7 mEq/L)
	*Massive PO intake (laxative abusers, accidental Epsom salts)
	*Magnesium enemas<ref>Schelling Fatal hypermagnesemia. JR1. Clin Nephrol. 2000 Jan;53(1):61-5.</ref>

	~~==Evaluation==~~
	{\| class="wikitable"		{\| class="wikitable"
	\|-		\|-
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	\| 12-15 \|\| [[Hypotension]], [[heart block]], [[Cardiac Arrest]], death		\| 12-15 \|\| [[Hypotension]], [[heart block]], [[Cardiac Arrest]], death
	\|}		\|}

			==Differential Diagnosis==
			*[[Renal Failure]]
			*[[Lithium]]
			*Volume depletion
			*[[Rhabdo]]
			*IV Mg (goal in PET/eclampsia 5-7 mEq/L)
			*Massive PO intake (laxative abusers, accidental Epsom salts)
			*Magnesium enemas<ref>Schelling Fatal hypermagnesemia. JR1. Clin Nephrol. 2000 Jan;53(1):61-5.</ref>

			==Evaluation==
			*Magnesium level

	==Management==		==Management==
	*[[IVF]]		*[[IVF]]
	*Furosemide 20-40mg IV		*[[Furosemide]] 20-40mg IV
	*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min		*[[CaCl]] 10% 5-10mL IV or [[Ca gluconate]] 10% 15-30mL IV over 5min
	*Consider HD for Mg >8 or poor renal function		*Consider hemodialysis for Mg >8 or poor renal function

	==Disposition==		==Disposition==


	==See Also==		==See Also==

2017-05-10T01:38:13Z

← Older revision		Revision as of 01:38, 10 May 2017
Line 5:		Line 5:

	==Clinical Features==		==Clinical Features==
	*~~Symptoms may be mild nausea~~ and vomiting ~~initially to~~ diaphragmatic paralysis ~~as the Mg concentration increases~~		*Nausea and vomiting
			*Loss of reflexes and diaphragmatic paralysis (at very high levels)

	==Differential Diagnosis==		==Differential Diagnosis==
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	==Management==		==Management==
	*[[IVF]] ~~(NS)~~		*[[IVF]]
	*Furosemide 20-40mg ~~IVP~~		*Furosemide 20-40mg IV
	*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min		*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min
	*Consider HD for Mg > 8 or poor renal function		*Consider HD for Mg >8 or poor renal function

	==Disposition==		==Disposition==

2017-05-09T22:50:12Z

← Older revision		Revision as of 22:50, 9 May 2017
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	*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min		*CaCl 10% 5-10mL IV or Ca gluconate 10% 15-30mL IV over 5min
	*Consider HD for Mg > 8 or poor renal function		*Consider HD for Mg > 8 or poor renal function

			==Disposition==


	==See Also==		==See Also==

2017-05-08T10:10:47Z

Causes of Hypermagnesemia

← Older revision		Revision as of 10:10, 8 May 2017
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	*Magnesium is an effective calcium channel blocker both extracellularly and intracellularly<ref>Rizzo MA, Fisher M, Lock JP. Hypermagnesemic pseudocoma. Arch Intern Med. 1993;153(9):1130.</ref>		*Magnesium is an effective calcium channel blocker both extracellularly and intracellularly<ref>Rizzo MA, Fisher M, Lock JP. Hypermagnesemic pseudocoma. Arch Intern Med. 1993;153(9):1130.</ref>
	*Intracellular magnesium profoundly blocks several cardiac potassium channels		*Intracellular magnesium profoundly blocks several cardiac potassium channels

	~~===Causes of Hypermagnesemia===~~
	*Renal insufficiency
	*IV magnesium infusion (e.g. in pregnancy/preeclampsia)
	*Oral ingestion, esp. if there is renal insufficiency
	** Epsom salts, laxatives

	==Clinical Features==		==Clinical Features==

← Older revision		Revision as of 22:17, 11 February 2021
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	*[[Electrolyte Abnormalities (Main)]]		*[[Electrolyte Abnormalities (Main)]]
	*[[Hypomagnesemia]]		*[[Hypomagnesemia]]
			*[[Preeclampsia]]

	==References==		==References==