IgA nephropathy - Revision history

ClaireLewis at 17:52, 16 October 2019

2019-10-16T17:52:00Z

← Older revision		Revision as of 17:52, 16 October 2019
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	*[[Hematuria]], persistent or recurrent, macroscopic or asymptomatic microscopic		*[[Hematuria]], persistent or recurrent, macroscopic or asymptomatic microscopic
	**Gross hematuria initially begins a few days after febrile illness, thus mimicking acute postinfectious glomerulonephritis		**Gross hematuria initially begins a few days after febrile illness, thus mimicking acute postinfectious glomerulonephritis
	*Mild proteinuria		*Mild [[proteinuria]]
	*+/- [[flank pain]], [[fever]] during acute episodes		*+/- [[flank pain]], [[fever]] during acute episodes
	*Usually slowly progressive, but rapidly progressive glomerulonephritis manifests initially in <10% of patients		*Usually slowly progressive, but rapidly progressive glomerulonephritis manifests initially in <10% of patients
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	==Evaluation==		==Evaluation==
	*[[UA]]		*[[UA]]
	**Hematuria, usually with dysmorphic RBCs, occasional RBC casts		**[[Hematuria]], usually with dysmorphic RBCs, occasional RBC casts
	**Mild proteinuria		**Mild [[proteinuria]]
	*BMP		*BMP
	**Creatinine usually normal unless progressed		**Creatinine usually normal unless progressed
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	==Disposition==		==Disposition==
	Discharge		*Discharge

	==See Also==		==See Also==

ClaireLewis: /* References */

2019-08-25T22:11:51Z

References

← Older revision		Revision as of 22:11, 25 August 2019
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	==References==		==References==
			https://www.merckmanuals.com/professional/genitourinary-disorders/glomerular-disorders/immunoglobulin-a-nephropathy
	<references/>		<references/>
	[[Category:Renal]]		[[Category:Renal]]

ClaireLewis: /* Clinical Features */

2019-08-25T22:11:35Z

Clinical Features

← Older revision		Revision as of 22:11, 25 August 2019
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	*Mild proteinuria		*Mild proteinuria
	*+/- [[flank pain]], [[fever]] during acute episodes		*+/- [[flank pain]], [[fever]] during acute episodes
	*Usually slowly progressive, but rapidly progressive glomerulonephritis manifests initially in <10% of patients		*Usually slowly progressive, but rapidly progressive glomerulonephritis manifests initially in <10% of patients

	~~Rapidly progressive GN is the initial manifestation in < 10% of patients.~~

	==Differential Diagnosis==		==Differential Diagnosis==

ClaireLewis: Created page with "==Background== Nephritic syndrome, form of chronic glomerulonephritis caused by deposition of IgA immune complexes in glomeruli Slowly progressive ==Clinical Features==..."

2019-08-25T22:11:16Z

Created page with "==Background== *Nephritic syndrome, form of chronic glomerulonephritis caused by deposition of IgA immune complexes in glomeruli *Slowly progressive ==Clinical Features==..."

New page

==Background==
*Nephritic syndrome, form of chronic [[glomerulonephritis]] caused by deposition of IgA immune complexes in glomeruli
*Slowly progressive

==Clinical Features==
*[[Hematuria]], persistent or recurrent, macroscopic or asymptomatic microscopic
**Gross hematuria initially begins a few days after febrile illness, thus mimicking acute postinfectious glomerulonephritis
*Mild proteinuria
*+/- [[flank pain]], [[fever]] during acute episodes
*Usually slowly progressive, but rapidly progressive glomerulonephritis manifests initially in <10% of patients

Rapidly progressive GN is the initial manifestation in < 10% of patients.

==Differential Diagnosis==
===Hematuria===
*Pediatric patients
**[[Glomerulonephritis]]
**[[UTI]]
**Congenital urinary tract anomaly
*Younger adults
**[[UTI]]
**[[Nephrolithiasis]]
*Older adults
**[[UTI]]
**Neoplasm
**[[BPH]]
*Any age
**[[Schistosomiasis]] (most common cause worldwide)

==Evaluation==
*[[UA]]
**Hematuria, usually with dysmorphic RBCs, occasional RBC casts
**Mild proteinuria
*BMP
**Creatinine usually normal unless progressed
*Definitive diagnosis with renal biopsy

==Management==
*Usually no treatment required in ED
*[[ACEi]] or [[ARB]] for hypertension, Cr >1.2, or macroalbuminuria
*[[Corticosteroids]] and/or [[cyclophosphamide]] for advanced or rapidly progressive disease

==Disposition==
Discharge

==See Also==
*[[Glomerulonephritis]]

==External Links==

==References==
<references/>
[[Category:Renal]]

IgA nephropathy - Revision history

ClaireLewis at 17:52, 16 October 2019

ClaireLewis: /* References */

ClaireLewis: /* Clinical Features */

ClaireLewis: Created page with "==Background== *Nephritic syndrome, form of chronic glomerulonephritis caused by deposition of IgA immune complexes in glomeruli *Slowly progressive ==Clinical Features==..."

ClaireLewis: Created page with "==Background== Nephritic syndrome, form of chronic glomerulonephritis caused by deposition of IgA immune complexes in glomeruli Slowly progressive ==Clinical Features==..."