https://wikem.org/w/index.php?action=history&feed=atom&title=Mycobacterium_avium_complex 2026-04-16T00:44:38Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Mycobacterium_avium_complex&diff=386755&oldid=prev 2026-03-20T11:11:32Z

<p>Remove non-existent Standard Template reference</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:11, 20 March 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{Standard Template}}</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Background==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Background==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Mycobacterium avium complex (MAC) is a group of mycobacteria including M. avium and M. intracellulare</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Mycobacterium avium complex (MAC) is a group of mycobacteria including M. avium and M. intracellulare</div></td></tr> </table>

Danbot https://wikem.org/w/index.php?title=Mycobacterium_avium_complex&diff=386713&oldid=prev 2026-03-20T11:03:48Z

<p>Create MAC page with AntibioticDose entries</p> <p><b>New page</b></p><div>{{Standard Template}}<br /> ==Background==<br /> *Mycobacterium avium complex (MAC) is a group of mycobacteria including M. avium and M. intracellulare<br /> *Ubiquitous environmental organism found in soil, water, and food<br /> *Primarily causes disseminated disease in immunocompromised patients (especially HIV with CD4 &lt;50)<br /> *Can also cause pulmonary disease in patients with underlying lung disease<br /> <br /> ==Clinical Features==<br /> *Fever, night sweats, weight loss<br /> *Fatigue and malaise<br /> *Abdominal pain, diarrhea<br /> *Lymphadenopathy, hepatosplenomegaly<br /> *Anemia and elevated alkaline phosphatase<br /> <br /> ==Differential Diagnosis==<br /> *[[Tuberculosis]]<br /> *[[Lymphoma]]<br /> *Other opportunistic infections in [[HIV]]<br /> <br /> ==Evaluation==<br /> *Blood cultures (mycobacterial)<br /> *CBC showing anemia<br /> *Elevated alkaline phosphatase, LDH<br /> *CT showing lymphadenopathy, hepatosplenomegaly<br /> <br /> ==Management==<br /> ===Primary Prophylaxis===<br /> *Indicated for HIV patients with CD4 &lt;50<br /> ====Adult====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=500mg PO q12h|context=Primary prophylaxis|disease=Mycobacterium avium complex|population=Adult}}<br /> *OR {{AntibioticDose|drug=Azithromycin|dose=1200mg PO weekly (Alt: 600mg PO twice weekly)|context=Primary prophylaxis|disease=Mycobacterium avium complex|population=Adult}}<br /> ====Pediatric====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=20mo-12yrs: 15mg/kg/day PO divided q12h (max 500mg/dose); &gt;13yrs: 500mg PO q12h|context=Primary prophylaxis, HIV|disease=Mycobacterium avium complex|population=Pediatric}}<br /> <br /> ===Treatment (Disseminated)===<br /> ====Adult====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=500mg PO q12h (use with ethambutol)|context=Treatment, disseminated|disease=Mycobacterium avium complex|population=Adult}}<br /> *OR {{AntibioticDose|drug=Azithromycin|dose=500-600mg PO daily (use with ethambutol; not 1st-line)|context=Treatment, disseminated|disease=Mycobacterium avium complex|population=Adult}}<br /> ====Pediatric====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=20mo-12yrs: 15-30mg/kg/day PO divided q12h (max 500mg/dose, use with ethambutol); &gt;13yrs: 500mg PO q12h (use with ethambutol)|context=Treatment, disseminated|disease=Mycobacterium avium complex|population=Pediatric}}<br /> <br /> ===Secondary Prophylaxis===<br /> ====Adult====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=500mg PO q12h (use with ethambutol)|context=Secondary prophylaxis|disease=Mycobacterium avium complex|population=Adult}}<br /> *OR {{AntibioticDose|drug=Azithromycin|dose=500-600mg PO daily (use with ethambutol; not 1st-line)|context=Secondary prophylaxis|disease=Mycobacterium avium complex|population=Adult}}<br /> ====Pediatric====<br /> *{{AntibioticDose|drug=Clarithromycin|dose=20mo-12yrs: 15mg/kg/day PO divided q12h (max 500mg/dose, use with ethambutol); &gt;13yrs: 500mg PO q12h (use with ethambutol)|context=Secondary prophylaxis, HIV|disease=Mycobacterium avium complex|population=Pediatric}}<br /> <br /> ==Disposition==<br /> *Admission for severe disseminated disease<br /> *Outpatient management for prophylaxis<br /> *Infectious disease consultation recommended<br /> <br /> ==See Also==<br /> *[[Tuberculosis]]<br /> *[[HIV]]<br /> *[[Neutropenic fever]]<br /> <br /> ==External Links==<br /> <br /> ==References==<br /> &lt;references/&gt;<br /> <br /> [[Category:Infectious Disease]]<br /> [[Category:Immunocompromised]]</div>

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