Mycophenolate mofetil - Revision history

Mholtz: Text replacement - " bid " to " BID "

2017-07-07T07:17:23Z

Text replacement - " bid " to " BID "

← Older revision		Revision as of 07:17, 7 July 2017
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	===Liver transplant rejection prophylaxis===		===Liver transplant rejection prophylaxis===
	*1.5 g PO ~~bid~~ or 1 g IV bid		*1.5 g PO BID or 1 g IV bid
	*Info: start IV with in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach		*Info: start IV with in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach

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	==Pediatric Dosing==		==Pediatric Dosing==
	===Kidney transplant rejection prophylaxis===		===Kidney transplant rejection prophylaxis===
	*3 mo-18 yo: Dose: 600mg/m^2 PO bid; Alt: 750mg PO ~~bid~~ for body surf. area = 1.25-1.5 m^2; 1 g PO ~~bid~~ for body surf. area >1.5 m^2; Max: 1 g/dose		*3 mo-18 yo: Dose: 600mg/m^2 PO bid; Alt: 750mg PO BID for body surf. area = 1.25-1.5 m^2; 1 g PO BID for body surf. area >1.5 m^2; Max: 1 g/dose

	==Special Populations==		==Special Populations==

Rossdonaldson1: Text replacement - " prednisone" to " prednisone"

2016-08-03T10:25:23Z

Text replacement - " prednisone" to " prednisone"

← Older revision		Revision as of 10:25, 3 August 2016
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	===Lupus nephritis===		===Lupus nephritis===
	*1 g PO bid		*1 g PO bid
	*Info: use with prednisone, consider decease dose 50% after 6mo treatment		*Info: use with [[prednisone]], consider decease dose 50% after 6mo treatment

	==Pediatric Dosing==		==Pediatric Dosing==

Rossdonaldson1: Text replacement - "HTN" to "hypertension"

2016-07-31T14:00:40Z

Text replacement - "HTN" to "hypertension"

← Older revision		Revision as of 14:00, 31 July 2016
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	===Common===		===Common===
	*~~HTN~~		*hypertension
	*infection		*infection
	*diarrhea		*diarrhea

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-19T16:30:30Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 16:30, 19 July 2016
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	==Administration==		==Administration==
	*Type: Immunosuppressant		*Type: Immunosuppressant
	*Dosage Forms: 250,500; ~~200 mg~~/mL; IV		*Dosage Forms: 250,500; 200mg/mL; IV
	*Routes of Administration: PO, IV		*Routes of Administration: PO, IV
	*Common Trade Names: CellCept		*Common Trade Names: CellCept
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	==Pediatric Dosing==		==Pediatric Dosing==
	===Kidney transplant rejection prophylaxis===		===Kidney transplant rejection prophylaxis===
	*3 mo-18 yo: Dose: ~~600 mg~~/m^2 PO bid; Alt: ~~750 mg~~ PO bid for body surf. area = 1.25-1.5 m^2; 1 g PO bid for body surf. area >1.5 m^2; Max: 1 g/dose		*3 mo-18 yo: Dose: 600mg/m^2 PO bid; Alt: 750mg PO bid for body surf. area = 1.25-1.5 m^2; 1 g PO bid for body surf. area >1.5 m^2; Max: 1 g/dose

	==Special Populations==		==Special Populations==
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	*Pediatric:		*Pediatric:
	**kidney transplant patients, delayed graft function immediate postop: no adjustment		**kidney transplant patients, delayed graft function immediate postop: no adjustment
	**kidney transplant patients, outside immediate post-transplant period: CrCl <30: max ~~600 mg~~/m^2/day; HD/PD: no supplement		**kidney transplant patients, outside immediate post-transplant period: CrCl <30: max 600mg/m^2/day; HD/PD: no supplement

	===Hepatic Dosing===		===Hepatic Dosing===

ClaireLewis: /* Serious */

2016-07-14T09:12:53Z

Serious

← Older revision		Revision as of 09:12, 14 July 2016
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	*colitis		*colitis
	*acute renal failure		*acute renal failure
	*interstitial lung dz		*interstitial lung disease
	*pregnancy loss, 1st trimester		*pregnancy loss, 1st trimester
	*congenital malformations		*congenital malformations

Rossdonaldson1: Text replacement - "tx" to "treatment"

2016-07-14T02:55:42Z

Text replacement - "tx" to "treatment"

← Older revision		Revision as of 02:55, 14 July 2016
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	===Lupus nephritis===		===Lupus nephritis===
	*1 g PO bid		*1 g PO bid
	*Info: use with prednisone, consider decease dose 50% after 6mo tx		*Info: use with prednisone, consider decease dose 50% after 6mo treatment

	==Pediatric Dosing==		==Pediatric Dosing==

ClaireLewis: /* Renal Dosing */

2016-07-14T01:41:25Z

Renal Dosing

← Older revision		Revision as of 01:41, 14 July 2016
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	===Renal Dosing===		===Renal Dosing===
	*Adult:		*Adult:
	**kidney transplant patients, delayed graft ~~fxn~~ immediate postop: no adjustment		**kidney transplant patients, delayed graft function immediate postop: no adjustment
	**kidney transplant patients, outside immediate post-transplant period:CrCl <25: max 1 g bid; HD/PD: no supplement		**kidney transplant patients, outside immediate post-transplant period:CrCl <25: max 1 g bid; HD/PD: no supplement
	**heart or liver transplant patients: CrCl <25: weigh risk/benefit; HD/PD: not defined		**heart or liver transplant patients: CrCl <25: weigh risk/benefit; HD/PD: not defined
	*Pediatric:		*Pediatric:
	**kidney transplant patients, delayed graft ~~fxn~~ immediate postop: no adjustment		**kidney transplant patients, delayed graft function immediate postop: no adjustment
	**kidney transplant patients, outside immediate post-transplant period: CrCl <30: max 600 mg/m^2/day; HD/PD: no supplement		**kidney transplant patients, outside immediate post-transplant period: CrCl <30: max 600 mg/m^2/day; HD/PD: no supplement

ClaireLewis: /* Contraindications */

2016-07-14T01:23:51Z

Contraindications

← Older revision		Revision as of 01:23, 14 July 2016
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	*caution in elderly patients		*caution in elderly patients
	*caution if GI disorder		*caution if GI disorder
	*caution if renal dz, severe		*caution if renal disease, severe
	*caution if bone marrow depression		*caution if bone marrow depression
	*caution if PKU (phenylalanine-containing forms)		*caution if PKU (phenylalanine-containing forms)

ClaireLewis: /* Special Populations */

2016-07-14T01:23:31Z

Special Populations

← Older revision		Revision as of 01:23, 14 July 2016
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	===Hepatic Dosing===		===Hepatic Dosing===
	*Adult: renal transplant with severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined		*Adult: renal transplant with severe hepatic parenchymal disease: no adjustment; other hepatic impairment: not defined
	*Pediatric: renal transplant with severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined		*Pediatric: renal transplant with severe hepatic parenchymal disease: no adjustment; other hepatic impairment: not defined

	==Contraindications==		==Contraindications==

Neil.m.young: Text replacement - " w/ " to " with "

2016-07-11T23:13:50Z

Text replacement - " w/ " to " with "

← Older revision		Revision as of 23:13, 11 July 2016
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	===Kidney transplant rejection prophylaxis===		===Kidney transplant rejection prophylaxis===
	*1 g PO/IV bid		*1 g PO/IV bid
	*Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach; stable patients may take w/ food		*Start: IV with in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach; stable patients may take with food

	===Heart transplant rejection prophylaxis===		===Heart transplant rejection prophylaxis===
	*1.5 g PO/IV bid		*1.5 g PO/IV bid
	*Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach		*Start: IV with in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach

	===Liver transplant rejection prophylaxis===		===Liver transplant rejection prophylaxis===
	*1.5 g PO bid or 1 g IV bid		*1.5 g PO bid or 1 g IV bid
	*Info: start IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach		*Info: start IV with in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach

	===Lupus nephritis===		===Lupus nephritis===
	*1 g PO bid		*1 g PO bid
	*Info: use w/ prednisone, consider decease dose 50% after 6mo tx		*Info: use with prednisone, consider decease dose 50% after 6mo tx

	==Pediatric Dosing==		==Pediatric Dosing==
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	===Hepatic Dosing===		===Hepatic Dosing===
	*Adult: renal transplant w/ severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined		*Adult: renal transplant with severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined
	*Pediatric: renal transplant w/ severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined		*Pediatric: renal transplant with severe hepatic parenchymal dz: no adjustment; other hepatic impairment: not defined

	==Contraindications==		==Contraindications==