Post-streptococcal glomerular nephritis - Revision history

ClaireLewis at 17:19, 16 October 2019

2019-10-16T17:19:22Z

← Older revision		Revision as of 17:19, 16 October 2019
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	==Clinical Features==		==Clinical Features==
	~~Most common:~~		*Varies from asymptomatic to microscopic [[hematuria]] to acute nephritic syndrome (gross hematuria, [[proteinuria]], edema, [[hypertension]], and [[acute kidney injury]])
	*~~Edema~~		*Most common features:
	*Gross hematuria		**Edema
	*Hypertension		**Gross [[hematuria]]
			**[[Hypertension]]
	Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)		*History of recent [[strep]] infection (e.g. [[strep pharyngitis]], [[impetigo]])

	~~Typically diagnosed by acute nephritis +~~ recent ~~GAS~~ infection ([[strep pharyngitis]], [[impetigo]])

	==Differential Diagnosis==		==Differential Diagnosis==
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	==Evaluation==		==Evaluation==
			*Typically diagnosed by acute nephritis + recent GAS infection ([[strep pharyngitis]], [[impetigo]])
	*CBC		*CBC
	*Chem 7		*Chem 7
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	**Sodium and water restriction		**Sodium and water restriction
	**[[Furosemide]] (also controls hypertension)		**[[Furosemide]] (also controls hypertension)
	***ACEi or CCBs for ~~HTN~~ not controlled by diuretics<ref>Geetha D et al. Poststreptococcal Glomerulonephritis Medication. eMedicine, Nov 2017. https://emedicine.medscape.com/article/240337-medication</ref>		***[[ACEi]] or [[CCBs]] for hypertension not controlled by diuretics<ref>Geetha D et al. Poststreptococcal Glomerulonephritis Medication. eMedicine, Nov 2017. https://emedicine.medscape.com/article/240337-medication</ref>
	**Consider dialysis (for acute renal failure)		**Consider [[dialysis]] (for acute [[renal failure]])

	==Disposition==		==Disposition==

Kxl328: /* Management */

2018-10-31T02:46:37Z

Management

← Older revision		Revision as of 02:46, 31 October 2018
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	*Supportive management (treat volume overload)		*Supportive management (treat volume overload)
	**Sodium and water restriction		**Sodium and water restriction
	**~~Lasix~~ (also controls hypertension)		**[[Furosemide]] (also controls hypertension)
	**Consider dialysis (for acute renal failure)		***ACEi or CCBs for HTN not controlled by diuretics<ref>Geetha D et al. Poststreptococcal Glomerulonephritis Medication. eMedicine, Nov 2017. https://emedicine.medscape.com/article/240337-medication</ref>
			**Consider dialysis (for acute renal failure)

	==Disposition==		==Disposition==

Rossdonaldson1: Text replacement - "UA" to "Urinalysis"

2016-10-02T14:20:55Z

Text replacement - "*UA" to "*Urinalysis"

← Older revision		Revision as of 14:20, 2 October 2016
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	*Streptozyme assay including ASO		*Streptozyme assay including ASO
	*Complement C3, C4, C50		*Complement C3, C4, C50
	*UA (dysmorphic red blood cells, varying degrees of proteinuria, red blood cell casts, and pyuria)		*[[Urinalysis]] (dysmorphic red blood cells, varying degrees of proteinuria, red blood cell casts, and pyuria)

	==Management==		==Management==

Rossdonaldson1: Text replacement - "HTN" to "hypertension"

2016-07-31T10:44:58Z

Text replacement - "HTN" to "hypertension"

← Older revision		Revision as of 10:44, 31 July 2016
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	*Supportive management (treat volume overload)		*Supportive management (treat volume overload)
	**Sodium and water restriction		**Sodium and water restriction
	**Lasix (also controls ~~HTN~~)		**Lasix (also controls hypertension)
	**Consider dialysis (for acute renal failure)		**Consider dialysis (for acute renal failure)

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-24T18:39:53Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 18:39, 24 July 2016
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	{{Glomerulonephritis causes}}		{{Glomerulonephritis causes}}

	==~~Diagnosis~~==		==Evaluation==
	*CBC		*CBC
	*Chem 7		*Chem 7

Ostermayer: Text replacement - "Category:Nephro" to "Category:Renal"

2016-03-22T14:08:32Z

Text replacement - "Category:Nephro" to "Category:Renal"

← Older revision		Revision as of 14:08, 22 March 2016
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	<references/>		<references/>

	[[Category:~~Nephro~~]]		[[Category:Renal]]
	[[Category:ID]]		[[Category:ID]]

Neil.m.young at 00:08, 22 February 2016

2016-02-22T00:08:14Z

← Older revision		Revision as of 00:08, 22 February 2016
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	==Diagnosis==		==Diagnosis==
	~~===Work-Up===~~
	*CBC		*CBC
	*Chem 7		*Chem 7

Kxl328 at 05:51, 21 February 2016

2016-02-21T05:51:46Z

← Older revision		Revision as of 05:51, 21 February 2016
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	Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)		Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)

	Typically diagnosed by acute nephritis + recent GAS infection (~~streptococcal~~ [[pharyngitis]], [[impetigo]])		Typically diagnosed by acute nephritis + recent GAS infection ([[strep pharyngitis]], [[impetigo]])

	==Differential Diagnosis==		==Differential Diagnosis==

Kxl328 at 05:50, 21 February 2016

2016-02-21T05:50:06Z

← Older revision		Revision as of 05:50, 21 February 2016
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	Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)		Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)

	Typically diagnosed by acute nephritis + recent GAS infection		Typically diagnosed by acute nephritis + recent GAS infection (streptococcal [[pharyngitis]], [[impetigo]])

	==Differential Diagnosis==		==Differential Diagnosis==

Neil.m.young: format

2015-08-18T04:05:41Z

format

← Older revision		Revision as of 04:05, 18 August 2015
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	==Background==		==Background==
	*Abbreviation: PSGN		*Abbreviation: PSGN
	*~~most~~ common cause of acute nephritis worldwide		*Most common cause of acute nephritis worldwide
	*~~risk~~ greatest in children 5-12 years old and adults >60		*Risk greatest in children 5-12 years old and adults >60
	*~~caused~~ by glomerular immune complex disease induced by specific nephritogenic strains of group A beta-hemolytic streptococcus (GAS)		*Caused by glomerular immune complex disease induced by specific nephritogenic strains of group A beta-hemolytic streptococcus (GAS)

	==~~Diagnosis~~==		==Clinical Features==
	Most common:		Most common:
	*~~edema~~		*Edema
	*~~gross~~ hematuria		*Gross hematuria
	*~~hypertension~~		*Hypertension

	Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)		Varies from asymptomatic to microscopic hematuria to acute nephritic syndrome (gross hematuria, proteinuria, edema, hypertension, and acute kidney injury)
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	Typically diagnosed by acute nephritis + recent GAS infection		Typically diagnosed by acute nephritis + recent GAS infection

	==Work-Up==		==Differential Diagnosis==
			{{Glomerulonephritis causes}}

			==Diagnosis==
			===Work-Up===
	*CBC		*CBC
	*Chem 7		*Chem 7
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	*UA (dysmorphic red blood cells, varying degrees of proteinuria, red blood cell casts, and pyuria)		*UA (dysmorphic red blood cells, varying degrees of proteinuria, red blood cell casts, and pyuria)

	==~~Differential Diagnosis==~~		==Management==
	~~{{Glomerulonephritis causes}}~~

	~~==Treatment~~==
	*Supportive management (treat volume overload)		*Supportive management (treat volume overload)
	** ~~sodium~~ and water restriction		**Sodium and water restriction
	** ~~lasix~~ (also controls HTN)		**Lasix (also controls HTN)
	** ~~consider~~ dialysis (for acute renal failure)		**Consider dialysis (for acute renal failure)

	==Disposition==		==Disposition==
	*~~most~~ have complete recovery, particularly children		*Most have complete recovery, particularly children
	*~~resolution~~ begins within the first two weeks		*Resolution begins within the first two weeks
	*~~small~~ subset have late renal complications (ie, hypertension, increasing proteinuria, and renal insufficiency)		*Small subset have late renal complications (ie, hypertension, increasing proteinuria, and renal insufficiency)

	==See Also==		==See Also==
	[[Strep_Pharyngitis\|Strep Pharyngitis]]		[[Strep_Pharyngitis\|Strep Pharyngitis]]

	==~~Source~~==		==References==
			<references/>

	[[Category:Nephro]]		[[Category:Nephro]]
	[[Category:ID]]		[[Category:ID]]