Post exposure prophylaxis antibiotics - Revision history

Ostermayer: /* Second Choice */

2024-10-29T18:03:12Z

Second Choice

← Older revision		Revision as of 18:03, 29 October 2024
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	===Second Choice===		===Second Choice===
	This alternative ~~regemin~~ is reserved for situations of HIV resistance or under infectious disease guidance		''This alternative drug choice is reserved for situations of HIV resistance or under infectious disease guidance''
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily
	PLUS		PLUS

Ostermayer: /* Treatment Regimens */

2024-10-29T18:02:21Z

Treatment Regimens

← Older revision		Revision as of 18:02, 29 October 2024
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	Post exposure prophylaxis is not recommended 72hrs post exposure<ref>CDC clinical guidelines https://www.cdc.gov/hivnexus/hcp/pep/index.html</ref> All regimens are 28 days duration.		Post exposure prophylaxis is not recommended 72hrs post exposure<ref>CDC clinical guidelines https://www.cdc.gov/hivnexus/hcp/pep/index.html</ref> All regimens are 28 days duration.
	===First Choice===		===First Choice===
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily		*[[Tenofovir]]-[[Emtricitabine]] (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily
	PLUS		PLUS
	*[[Raltegravir]] (RAL)(400 mg) twice daily or [[Dolutegravir]] (DTG)(50 mg) once daily		*[[Raltegravir]] (RAL)(400 mg) twice daily or [[Dolutegravir]] (DTG)(50 mg) once daily

Ostermayer: /* Treatment Regimens */

2024-10-29T18:01:59Z

Treatment Regimens

← Older revision		Revision as of 18:01, 29 October 2024
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	==Treatment Regimens==		==Treatment Regimens==
	~~post~~ exposure prophylaxis is not recommended 72hrs post exposure<ref>CDC clinical guidelines https://www.cdc.gov/hivnexus/hcp/pep/index.html</ref>		Post exposure prophylaxis is not recommended 72hrs post exposure<ref>CDC clinical guidelines https://www.cdc.gov/hivnexus/hcp/pep/index.html</ref> All regimens are 28 days duration.
	===~~2 drug Basic~~===		===First Choice===
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily ~~'''OR'''~~		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily
	*~~Zidovudine–lamivudine~~ (~~Combivir~~) ~~one tablet~~ (~~300mg of zidovudine with 150mg of lamivudine~~) twice daily		PLUS
	**this regimen is preferred in pregnancy		*[[Raltegravir]] (RAL)(400 mg) twice daily or [[Dolutegravir]] (DTG)(50 mg) once daily

	===~~3 drug Expanded<ref name="NEJM"></ref>~~===		===Second Choice===
	*~~[[Ritonavir–lopinavir]]~~ (~~Kaletra~~) ~~PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)~~		This alternative regemin is reserved for situations of HIV resistance or under infectious disease guidance
	**Two tablets (~~50mg~~ of ~~ritonavir~~ with 200mg of ~~lopinavir per tablet~~) ~~twice daily, or four tablets~~ once daily		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily
	*~~Ritonavir plus atazanavir~~ (~~plus either tenofovir–emtricitabine or zidovudine–lamivudine~~		PLUS
	**100mg of ritonavir plus 300mg of atazanavir once daily		*[[Darunavir]] (DRV)(800 mg) once daily with [[Ritonavir]] (RTV)(100 mg) once daily
	*Ritonavir ~~plus darunavir~~ (~~plus either tenofovir–emtricitabine or zidovudine–lamivudine~~)
	**100mg of ritonavir plus two tablets, each containing 400mg of darunavir, once daily

	==[[Meningitis\|Neisseria meningitidis]]==		==[[Meningitis\|Neisseria meningitidis]]==

Ostermayer: /* Treatment Regimens */

2024-10-29T17:52:35Z

Treatment Regimens

← Older revision		Revision as of 17:52, 29 October 2024
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	==Treatment Regimens==		==Treatment Regimens==
	not recommended 72hrs post exposure<ref ~~name="NEJM"~~>~~Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http~~://www.~~uphs.upenn~~.~~edu~~/~~ppmc_emergency~~/~~PPMC%20Bookmarks~~/~~2012%20LLSA%20Articles~~/~~Postexposure%20Prophylaxis%20for%20HIV~~.~~pdf PDF]~~</ref>		post exposure prophylaxis is not recommended 72hrs post exposure<ref>CDC clinical guidelines https://www.cdc.gov/hivnexus/hcp/pep/index.html</ref>
	===2 drug Basic===		===2 drug Basic===
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''

Ostermayer: /* Treatment Regimens */

2024-10-29T17:51:53Z

Treatment Regimens

← Older revision		Revision as of 17:51, 29 October 2024
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	==Treatment Regimens==		==Treatment Regimens==
	~~===2 drug Basic~~<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>===		not recommended 72hrs post exposure<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>
			===2 drug Basic===
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''
	*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily		*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily

Ihearttroponin: /* 3 drug Expanded */

2020-03-22T19:05:30Z

3 drug Expanded

← Older revision		Revision as of 19:05, 22 March 2020
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	===3 drug Expanded<ref name="NEJM"></ref>===		===3 drug Expanded<ref name="NEJM"></ref>===
	*Ritonavir–lopinavir (Kaletra) PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)		*[[Ritonavir–lopinavir]] (Kaletra) PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)
	**Two tablets (50mg of ritonavir with 200mg of lopinavir per tablet) twice daily, or four tablets once daily		**Two tablets (50mg of ritonavir with 200mg of lopinavir per tablet) twice daily, or four tablets once daily
	*Ritonavir plus atazanavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine		*Ritonavir plus atazanavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine

Rossdonaldson1 at 20:22, 15 April 2019

2019-04-15T20:22:50Z

← Older revision		Revision as of 20:22, 15 April 2019
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	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''
	*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily		*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily
	**this regimen is preferred in ~~pregancy~~		**this regimen is preferred in pregnancy

	===3 drug Expanded<ref name="NEJM"></ref>===		===3 drug Expanded<ref name="NEJM"></ref>===

Rossdonaldson1 at 20:22, 15 April 2019

2019-04-15T20:22:37Z

← Older revision		Revision as of 20:22, 15 April 2019
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	==[[Meningitis\|Neisseria meningitidis]]==		==[[Meningitis\|Neisseria meningitidis]]==
	{{Neisseria meningitis post exposure prophylaxis}}		{{Neisseria meningitis post exposure prophylaxis}}

	==See Also==		==See Also==
	{{Antibiotics by diagnosis navigation}}		{{Antibiotics by diagnosis navigation}}

	=References=		==References==
	<references/>		<references/>
	[[Category:ID]] [[Category:Pharmacology]]		[[Category:ID]] [[Category:Pharmacology]]

Mholtz: Text replacement - "OR" to "'''OR'''"

2017-05-30T22:54:51Z

Text replacement - "OR" to "'''OR'''"

← Older revision		Revision as of 22:54, 30 May 2017
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	==Treatment Regimens==		==Treatment Regimens==
	===2 drug Basic<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>===		===2 drug Basic<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>===
	*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily OR		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily '''OR'''
	*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily		*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily
	**this regimen is preferred in pregancy		**this regimen is preferred in pregancy

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-21T09:36:22Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 09:36, 21 July 2016
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	==Treatment Regimens==		==Treatment Regimens==
	===2 drug Basic<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>===		===2 drug Basic<ref name="NEJM">Landovitz RJ, Currier JS. Postexposure prophylaxis for HIV infection. N Eng J Med. 2009 Oct 29; 361(18): 1768-75. [http://www.uphs.upenn.edu/ppmc_emergency/PPMC%20Bookmarks/2012%20LLSA%20Articles/Postexposure%20Prophylaxis%20for%20HIV.pdf PDF]</ref>===
	*Tenofovir-Emtricitabine (Truvada) one tablet (~~300 mg~~ of tenofovir with ~~200 mg~~ of emtricitabine) once daily OR		*Tenofovir-Emtricitabine (Truvada) one tablet (300mg of tenofovir with 200mg of emtricitabine) once daily OR
	*Zidovudine–lamivudine (Combivir) one tablet (~~300 mg~~ of zidovudine with ~~150 mg~~ of lamivudine) twice daily		*Zidovudine–lamivudine (Combivir) one tablet (300mg of zidovudine with 150mg of lamivudine) twice daily
	**this regimen is preferred in pregancy		**this regimen is preferred in pregancy

	===3 drug Expanded<ref name="NEJM"></ref>===		===3 drug Expanded<ref name="NEJM"></ref>===
	*Ritonavir–lopinavir (Kaletra) PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)		*Ritonavir–lopinavir (Kaletra) PLUS either tenofovir–emtricitabine or zidovudine–lamivudine)
	**Two tablets (~~50 mg~~ of ritonavir with ~~200 mg~~ of lopinavir per tablet) twice daily, or four tablets once daily		**Two tablets (50mg of ritonavir with 200mg of lopinavir per tablet) twice daily, or four tablets once daily
	*Ritonavir plus atazanavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine		*Ritonavir plus atazanavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine
	**~~100 mg~~ of ritonavir plus ~~300 mg~~ of atazanavir once daily		**100mg of ritonavir plus 300mg of atazanavir once daily
	*Ritonavir plus darunavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine)		*Ritonavir plus darunavir (plus either tenofovir–emtricitabine or zidovudine–lamivudine)
	**~~100 mg~~ of ritonavir plus two tablets, each containing ~~400 mg~~ of darunavir, once daily		**100mg of ritonavir plus two tablets, each containing 400mg of darunavir, once daily

	==[[Meningitis\|Neisseria meningitidis]]==		==[[Meningitis\|Neisseria meningitidis]]==