Proctitis - Revision history

Danbot: Add Doxycycline AntibioticDose entries

2026-03-20T11:00:39Z

Add Doxycycline AntibioticDose entries

← Older revision		Revision as of 11:00, 20 March 2026
Line 1:		Line 1:
	<languages/>		<languages/>
	~~<translate>~~

	==Background==		==Background==
Line 11:		Line 11:
	*Vasculitis		*Vasculitis
	*Ischemia		*Ischemia
	*Infectious ([[~~Special:MyLanguage/~~STI\|STI]] and enteric organisms)		*Infectious ([[STI\|STI]] and enteric organisms)


Line 23:		Line 23:
	*Tenesmus		*Tenesmus
	*Mucoid discharge		*Mucoid discharge
	*Inguinal lymphadenopathy (may be seen with [[~~Special:MyLanguage/~~Syphilis\|T. pallidum]])		*Inguinal lymphadenopathy (may be seen with [[Syphilis\|T. pallidum]])


	===By Causative Agent===		===By Causative Agent===

	*[[~~Special:MyLanguage/~~Condyloma Acuminata\|Condyloma Acuminata]]		*[[Condyloma Acuminata\|Condyloma Acuminata]]
	*[[~~Special:MyLanguage/~~Gonorrhea\|Gonorrhea]]		*[[Gonorrhea\|Gonorrhea]]
	**Symptoms vary from none to severe rectal pain with yellow, bloody discharge		**Symptoms vary from none to severe rectal pain with yellow, bloody discharge
	**Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt		**Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt
	*[[~~Special:MyLanguage/~~Chlamydia\|Chlamydia]]		*[[Chlamydia\|Chlamydia]]
	**Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics		**Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics
	**Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge		**Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge
	**Lymphogranulomatous variety		**Lymphogranulomatous variety
	***Acutely painful anal ulcerations associated with unilateral lymph node enlargement		***Acutely painful anal ulcerations associated with unilateral lymph node enlargement
	***[[~~Special:MyLanguage/~~Fever\|Fever]] and flulike symptoms		***[[Fever\|Fever]] and flulike symptoms
	***May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas		***May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
	*[[~~Special:MyLanguage/~~Syphilis\|Syphilis]]		*[[Syphilis\|Syphilis]]
	**Primary		**Primary
	***Anal chancres appear ~2-6 weeks after intercourse, are often painful		***Anal chancres appear ~2-6 weeks after intercourse, are often painful
Line 47:		Line 47:
	**Secondary		**Secondary
	***Condylomata lata (flatter and firmer than condylomata acuminata)		***Condylomata lata (flatter and firmer than condylomata acuminata)
	*[[~~Special:MyLanguage/~~Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]		*[[Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]
	**Itching and soreness in perianal area progressing to severe anorectal pain		**Itching and soreness in perianal area progressing to severe anorectal pain
	***Accompanied by flulike illness, inguinal adenopathy		***Accompanied by flulike illness, inguinal adenopathy
Line 56:		Line 56:
	==Differential Diagnosis==		==Differential Diagnosis==

	~~</translate>~~
	{{Anorectal DDX}}		{{Anorectal DDX}}
	~~<translate>~~


Line 68:		Line 68:
	==Management==		==Management==

	~~</translate>~~
	{{Presumed GC chlamydia of cervix, urethra, or rectum}}		{{Presumed GC chlamydia of cervix, urethra, or rectum}}
	~~<translate>~~


	~~===[[Special:MyLanguage/Syphilis\|Syphilis]]===~~

	*[[~~Special:MyLanguage/Penicillin~~\|~~Penicillin~~]] ~~G 2.4mil IM x1~~		===[[Syphilis\|Syphilis]]===

			*[[Penicillin\|Penicillin]] G 2.4mil IM x1

	~~===[[Special:MyLanguage/Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]===~~

	*[[~~Special:MyLanguage/Acyclovir~~\|~~Acyclovir~~]] ~~400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes~~		===[[Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]===

			*[[Acyclovir\|Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

	===[[~~Special:MyLanguage/~~Lymphogranuloma Venereum\|Lymphogranuloma Venereum]]===
			===[[Lymphogranuloma Venereum\|Lymphogranuloma Venereum]]===

	*Consider in patients with bloody discharge, perianal or mucosal ulcers, chlamydia NAAT+, and MSM		*Consider in patients with bloody discharge, perianal or mucosal ulcers, chlamydia NAAT+, and MSM
	*Extend [[~~Special:MyLanguage/~~doxycycline\|doxycycline]] 100mg PO BID for 21 days total<ref>Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1</ref>		*Extend [[doxycycline\|doxycycline]] 100mg PO BID for 21 days total<ref>Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1</ref>



			===Antibiotic Dosing===
			====Adult====
			*{{AntibioticDose\|drug=Doxycycline\|dose=100mg PO q12h x 7 days\|context=Proctitis\|disease=Proctitis\|population=Adult}}
			====Pediatric====
			*{{AntibioticDose\|drug=Doxycycline\|dose=Adolescents; 100mg PO q12h x 7 days\|context=Proctitis\|disease=Proctitis\|population=Pediatric}}

	==Disposition==		==Disposition==
Line 94:		Line 101:
	==See Also==		==See Also==

	*[[~~Special:MyLanguage/~~Anorectal Disorders\|Anorectal Disorders]]		*[[Anorectal Disorders\|Anorectal Disorders]]


Line 104:		Line 111:
	<references/>		<references/>
	[[Category:GI]]		[[Category:GI]]
	~~</translate>~~

Ostermayer: Prepared the page for translation

2026-01-04T23:54:33Z

Prepared the page for translation

← Older revision		Revision as of 23:54, 4 January 2026
Line 1:		Line 1:
			<languages/>
			<translate>

	==Background==		==Background==


	===Causes===		===Causes===

	*Radiation treatment		*Radiation treatment
	*Autoimmune		*Autoimmune
	*Vasculitis		*Vasculitis
	*Ischemia		*Ischemia
	*Infectious ([[STI]] and enteric organisms)		*Infectious ([[Special:MyLanguage/STI\|STI]] and enteric organisms)


	==Clinical Features==		==Clinical Features==


	===General===		===General===

	*Inflammation of the rectal mucosa		*Inflammation of the rectal mucosa
	*Pain on defecation		*Pain on defecation
	*Tenesmus		*Tenesmus
	*Mucoid discharge		*Mucoid discharge
	*Inguinal lymphadenopathy (may be seen with [[Syphilis\|T. pallidum]])		*Inguinal lymphadenopathy (may be seen with [[Special:MyLanguage/Syphilis\|T. pallidum]])


	===By Causative Agent===		===By Causative Agent===
	*[[Condyloma Acuminata]]
	*[[Gonorrhea]]		*[[Special:MyLanguage/Condyloma Acuminata\|Condyloma Acuminata]]
			*[[Special:MyLanguage/Gonorrhea\|Gonorrhea]]
	**Symptoms vary from none to severe rectal pain with yellow, bloody discharge		**Symptoms vary from none to severe rectal pain with yellow, bloody discharge
	**Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt		**Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt
	*[[Chlamydia]]		*[[Special:MyLanguage/Chlamydia\|Chlamydia]]
	**Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics		**Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics
	**Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge		**Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge
	**Lymphogranulomatous variety		**Lymphogranulomatous variety
	***Acutely painful anal ulcerations associated with unilateral lymph node enlargement		***Acutely painful anal ulcerations associated with unilateral lymph node enlargement
	***[[Fever]] and flulike symptoms		***[[Special:MyLanguage/Fever\|Fever]] and flulike symptoms
	***May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas		***May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
	*[[Syphilis]]		*[[Special:MyLanguage/Syphilis\|Syphilis]]
	**Primary		**Primary
	***Anal chancres appear ~2-6 weeks after intercourse, are often painful		***Anal chancres appear ~2-6 weeks after intercourse, are often painful
Line 35:		Line 47:
	**Secondary		**Secondary
	***Condylomata lata (flatter and firmer than condylomata acuminata)		***Condylomata lata (flatter and firmer than condylomata acuminata)
	*[[Herpes Simplex Virus-2]]		*[[Special:MyLanguage/Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]
	**Itching and soreness in perianal area progressing to severe anorectal pain		**Itching and soreness in perianal area progressing to severe anorectal pain
	***Accompanied by flulike illness, inguinal adenopathy		***Accompanied by flulike illness, inguinal adenopathy
	**Early lesions are small, discrete vesicles on erythematous base		**Early lesions are small, discrete vesicles on erythematous base
	***Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers		***Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers


	==Differential Diagnosis==		==Differential Diagnosis==

			</translate>
	{{Anorectal DDX}}		{{Anorectal DDX}}
			<translate>


	==Evaluation==		==Evaluation==

	*Consider Gram stain and culture		*Consider Gram stain and culture


	==Management==		==Management==

			</translate>
	{{Presumed GC chlamydia of cervix, urethra, or rectum}}		{{Presumed GC chlamydia of cervix, urethra, or rectum}}
			<translate>


			===[[Special:MyLanguage/Syphilis\|Syphilis]]===

			*[[Special:MyLanguage/Penicillin\|Penicillin]] G 2.4mil IM x1


			===[[Special:MyLanguage/Herpes Simplex Virus-2\|Herpes Simplex Virus-2]]===

			*[[Special:MyLanguage/Acyclovir\|Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

	~~===[[Syphilis]]===~~
	*[[Penicillin]] G 2.4mil IM x1

	===[[~~Herpes Simplex Virus-2~~]]===		===[[Special:MyLanguage/Lymphogranuloma Venereum\|Lymphogranuloma Venereum]]===
	*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

	~~===[[Lymphogranuloma Venereum]]===~~
	*Consider in patients with bloody discharge, perianal or mucosal ulcers, chlamydia NAAT+, and MSM		*Consider in patients with bloody discharge, perianal or mucosal ulcers, chlamydia NAAT+, and MSM
	*Extend [[doxycycline]] 100mg PO BID for 21 days total<ref>Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1</ref>		*Extend [[Special:MyLanguage/doxycycline\|doxycycline]] 100mg PO BID for 21 days total<ref>Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1</ref>


	==Disposition==		==Disposition==


	==See Also==		==See Also==
	*[[Anorectal Disorders]]
			*[[Special:MyLanguage/Anorectal Disorders\|Anorectal Disorders]]


	==External Links==		==External Links==


	==References==		==References==

	<references/>		<references/>
	[[Category:GI]]		[[Category:GI]]
			</translate>

Athorne: /* Management */

2021-07-30T05:06:44Z

Management

← Older revision		Revision as of 05:06, 30 July 2021
Line 55:		Line 55:
	===[[Herpes Simplex Virus-2]]===		===[[Herpes Simplex Virus-2]]===
	*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes		*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

			===[[Lymphogranuloma Venereum]]===
			*Consider in patients with bloody discharge, perianal or mucosal ulcers, chlamydia NAAT+, and MSM
			*Extend [[doxycycline]] 100mg PO BID for 21 days total<ref>Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1</ref>

	==Disposition==		==Disposition==

Rossdonaldson1: /* Evaluation */

2020-12-23T19:18:28Z

Evaluation

@@ Line 45: / Line 45: @@
 ==Evaluation==
+*Consider Gram stain and culture
 ==Management==

Rossdonaldson1: /* Clinical Features */

2020-12-23T19:17:18Z

Clinical Features

@@ Line 8: / Line 8: @@
 ==Clinical Features==
 *Inflammation of the rectal mucosa
 *Pain on defecation
@@ Line 13: / Line 14: @@
 *Mucoid discharge
 *Inguinal lymphadenopathy (may be seen with [[Syphilis|T. pallidum]])
 ==Differential Diagnosis==

Rossdonaldson1: /* See Also */

2020-12-23T19:15:21Z

Rossdonaldson1: /* Management */

2020-12-23T19:15:09Z

Management

← Older revision		Revision as of 19:15, 23 December 2020
Line 58:		Line 58:
	===[[Herpes Simplex Virus-2]]===		===[[Herpes Simplex Virus-2]]===
	*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes		*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

			==Disposition==

	==See Also==		==See Also==

Rossdonaldson1: /* Evaluation */

2020-12-23T19:14:31Z

Evaluation

← Older revision		Revision as of 19:14, 23 December 2020
Line 43:		Line 43:
	*Secondary		*Secondary
	**Condylomata lata (flatter and firmer than condylomata acuminata)		**Condylomata lata (flatter and firmer than condylomata acuminata)
	*Treatment
	**[[Penicillin]] G 2.4mil IM x1

	===[[Herpes Simplex Virus-2]]===		===[[Herpes Simplex Virus-2]]===
Line 51:		Line 49:
	*Early lesions are small, discrete vesicles on erythematous base		*Early lesions are small, discrete vesicles on erythematous base
	**Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers		**Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers
	*Treatment
	**[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

	==Management==		==Management==

Rossdonaldson1: /* Management */

2020-12-23T19:14:09Z

Management

← Older revision		Revision as of 19:14, 23 December 2020
Line 56:		Line 56:
	==Management==		==Management==
	{{Presumed GC chlamydia of cervix, urethra, or rectum}}		{{Presumed GC chlamydia of cervix, urethra, or rectum}}

			===[[Syphilis]]===
			*[[Penicillin]] G 2.4mil IM x1

			===[[Herpes Simplex Virus-2]]===
			*[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

	==See Also==		==See Also==

Rossdonaldson1: /* Management */

2020-12-23T19:13:43Z

Management

← Older revision		Revision as of 19:13, 23 December 2020
Line 19:		Line 19:
	==Evaluation==		==Evaluation==

	~~==Management==~~
	===[[Condyloma Acuminata]]===		===[[Condyloma Acuminata]]===

Line 27:		Line 26:
	*Diagnosis made by Gram stain and culture		*Diagnosis made by Gram stain and culture
	*Also consider dissemination to heart, liver, CNS, and joints		*Also consider dissemination to heart, liver, CNS, and joints
	*Treatment: [[ceftriaxone]] 125mg IM + [[azithromycin]] 2gm PO single dose


	===[[Chlamydia]]===		===[[Chlamydia]]===
Line 37:		Line 34:
	**[[Fever]] and flulike symptoms		**[[Fever]] and flulike symptoms
	**May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas		**May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
	*Treatment
	**Non-LGV: [[Azithromycin]] 2gm PO x1 or [[doxycycline]] 100mg PO BID x7d
	**LGV: [[Doxycyline]] 100mg PO BID x21d
	===[[Syphilis]]===		===[[Syphilis]]===
	*Primary		*Primary

← Older revision		Revision as of 19:15, 23 December 2020
Line 63:		Line 63:
	==See Also==		==See Also==
	*[[Anorectal Disorders]]		*[[Anorectal Disorders]]

			==External Links==

	==References==		==References==
	<references/>		<references/>
	[[Category:GI]]		[[Category:GI]]