Template:Endometritis Antibiotics - Revision history

Danbot: Convert to AntibioticDose template for SMW integration

2026-03-20T02:24:21Z

Convert to AntibioticDose template for SMW integration

← Older revision		Revision as of 02:24, 20 March 2026
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	====<48hrs Post Partum====		====<48hrs Post Partum====
	''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''		''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''
	*(~~Prefered~~ first line) {{AntibioticDose\|disease=Postpartum endometritis\|drug=Clindamycin\|dose=900mg IV q8hrs\|context=~~First~~ line ~~less than~~ 48hrs postpartum~~\|population=Adult~~}} PLUS {{AntibioticDose\|disease=Postpartum endometritis\|drug=Gentamicin\|dose=5mg/kg IV q24hrs or 1.5mg/kg IV q8hrs\|context=~~First line less than~~ 48hrs postpartum ~~with Clindamycin\|population=Adult~~}}<ref>Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613</ref> OR		*(Preferred first line) {{AntibioticDose\|disease=Postpartum endometritis\|drug=Clindamycin\|dose=900mg IV q8hrs\|context=Preferred first line; <48hrs postpartum}} PLUS {{AntibioticDose\|disease=Postpartum endometritis\|drug=Gentamicin\|dose=5mg/kg IV q24hrs or 1.5mg/kg IV q8hrs\|context=Combined with Clindamycin; <48hrs postpartum}}<ref>Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613</ref> OR
	*[[Doxycycline]] 100mg IV PO q12hrs ~~daily~~ PLUS		*{{AntibioticDose\|disease=Postpartum endometritis\|drug=Doxycycline\|dose=100mg IV/PO q12hrs\|context=<48hrs postpartum; combined with Ampicillin/Sulbactam or Cefoxitin}} PLUS
	**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Ampicillin/Sulbactam\|dose=3g IV q6hrs\|context=~~Alt less than~~ 48hrs postpartum with Doxycycline~~\|population=Adult~~}}		**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Ampicillin/Sulbactam\|dose=3g IV q6hrs\|context=<48hrs postpartum; combined with Doxycycline}}
	**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Cefoxitin\|dose=2g IV q6hrs\|context=~~Alt less than~~ 48hrs postpartum with Doxycycline~~\|population=Adult~~}}		**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Cefoxitin\|dose=2g IV q6hrs\|context=<48hrs postpartum; combined with Doxycycline}}

	====>48hrs Post Partum====		====>48hrs Post Partum====
	*{{AntibioticDose\|disease=Postpartum endometritis\|drug=Doxycycline\|dose=100mg IV or PO q12hrs\|context=~~Greater than~~ 48hrs postpartum~~\|population=Adult~~}} + {{AntibioticDose\|disease=Postpartum endometritis\|drug=Metronidazole\|dose=500mg IV or PO q8hrs\|context=~~Greater than~~ 48hrs postpartum with Doxycycline~~\|population=Adult~~}}		*{{AntibioticDose\|disease=Postpartum endometritis\|drug=Doxycycline\|dose=100mg IV or PO q12hrs\|context=>48hrs postpartum; combined with Metronidazole}} + {{AntibioticDose\|disease=Postpartum endometritis\|drug=Metronidazole\|dose=500mg IV or PO q8hrs\|context=>48hrs postpartum; combined with Doxycycline}}
	**Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations		**Use Metronidazole with caution in breastfeeding mothers as its active metabolite is present in breast milk at concentrations similar to maternal plasma concentrations

Danbot: Convert to AntibioticDose template with disease=Postpartum endometritis for SMW linking

2026-03-20T01:17:15Z

Convert to AntibioticDose template with disease=Postpartum endometritis for SMW linking

← Older revision		Revision as of 01:17, 20 March 2026
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	====<48hrs Post Partum====		====<48hrs Post Partum====
	''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''		''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''
	*(Prefered first line) [[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 5mg/kg IV ~~q24hours (same efficacy and more cost effective vs. 1.5mg/kg)~~ or 1.5mg/kg IV q8hrs<ref>Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613</ref> OR		*(Prefered first line) {{AntibioticDose\|disease=Postpartum endometritis\|drug=Clindamycin\|dose=900mg IV q8hrs\|context=First line less than 48hrs postpartum\|population=Adult}} PLUS {{AntibioticDose\|disease=Postpartum endometritis\|drug=Gentamicin\|dose=5mg/kg IV q24hrs or 1.5mg/kg IV q8hrs\|context=First line less than 48hrs postpartum with Clindamycin\|population=Adult}}<ref>Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613</ref> OR
	*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS		*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS
	**[[Ampicillin/Sulbactam]] 3g IV q6hrs		**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Ampicillin/Sulbactam\|dose=3g IV q6hrs\|context=Alt less than 48hrs postpartum with Doxycycline\|population=Adult}}
	**[[Cefoxitin]] 2g IV q6hrs ~~daily~~		**{{AntibioticDose\|disease=Postpartum endometritis\|drug=Cefoxitin\|dose=2g IV q6hrs\|context=Alt less than 48hrs postpartum with Doxycycline\|population=Adult}}

	====>48hrs Post Partum====		====>48hrs Post Partum====
	*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs ~~daily~~		*{{AntibioticDose\|disease=Postpartum endometritis\|drug=Doxycycline\|dose=100mg IV or PO q12hrs\|context=Greater than 48hrs postpartum\|population=Adult}} + {{AntibioticDose\|disease=Postpartum endometritis\|drug=Metronidazole\|dose=500mg IV or PO q8hrs\|context=Greater than 48hrs postpartum with Doxycycline\|population=Adult}}
	**Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations		**Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations

Rossdonaldson1: /* >48hrs Post Partum */

2022-07-06T21:50:10Z

>48hrs Post Partum

← Older revision		Revision as of 21:50, 6 July 2022
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	====>48hrs Post Partum====		====>48hrs Post Partum====
	*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily		*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily
	**''Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations ~~(Gray 1961; Heisterberg 1983; Passmore 1988)''~~		**Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations

Rossdonaldson1: /* >48hrs Post Partum */

2022-07-06T21:49:31Z

>48hrs Post Partum

← Older revision		Revision as of 21:49, 6 July 2022
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	====>48hrs Post Partum====		====>48hrs Post Partum====
	''Use Metronidazole with caution in breastfeeding mothers as Metronidazole and its active hydroxyl metabolite are present in breast milk at concentrations similar to maternal plasma concentrations. Metronidazole and its active metabolite can be detected in the serum of breastfeeding infants (Gray 1961; Heisterberg 1983; Passmore 1988)''
	*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily		*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily
			**''Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations (Gray 1961; Heisterberg 1983; Passmore 1988)''

Rossdonaldson1: /* <48hrs Post Partum */

2022-07-06T21:39:09Z

<48hrs Post Partum

← Older revision		Revision as of 21:39, 6 July 2022
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	====<48hrs Post Partum====		====<48hrs Post Partum====
	''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''		''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''
	*(Prefered first line) [[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 5mg/kg IV q24hours (same efficacy and more cost effective vs. 1.5mg/kg) or 1.5mg/kg IV q8hrs OR		*(Prefered first line) [[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 5mg/kg IV q24hours (same efficacy and more cost effective vs. 1.5mg/kg) or 1.5mg/kg IV q8hrs<ref>Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613</ref> OR
	*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS		*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS
	**[[Ampicillin/Sulbactam]] 3g IV q6hrs		**[[Ampicillin/Sulbactam]] 3g IV q6hrs

Jsenvisky: /* >48hrs Post Partum */

2022-06-28T17:40:48Z

>48hrs Post Partum

← Older revision		Revision as of 17:40, 28 June 2022
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	====<48hrs Post Partum====		====<48hrs Post Partum====
	''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''		''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''
	*[[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 1.5mg/kg IV q8hrs OR		*(Prefered first line) [[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 5mg/kg IV q24hours (same efficacy and more cost effective vs. 1.5mg/kg) or 1.5mg/kg IV q8hrs OR
	*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS		*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS
	**[[Ampicillin/Sulbactam]] 3g IV q6hrs		**[[Ampicillin/Sulbactam]] 3g IV q6hrs
Line 7:		Line 7:

	====>48hrs Post Partum====		====>48hrs Post Partum====
			''Use Metronidazole with caution in breastfeeding mothers as Metronidazole and its active hydroxyl metabolite are present in breast milk at concentrations similar to maternal plasma concentrations. Metronidazole and its active metabolite can be detected in the serum of breastfeeding infants (Gray 1961; Heisterberg 1983; Passmore 1988)''
	*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily		*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily

Kxl328 at 15:31, 17 August 2015

2015-08-17T15:31:33Z

← Older revision		Revision as of 15:31, 17 August 2015
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	====<48hrs Post Partum====		====<48hrs Post Partum====
	''Treatment is targeted against ~~molymicrobial~~ infections''		''Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora''
	*[[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 1.5mg/kg IV q8hrs OR		*[[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 1.5mg/kg IV q8hrs OR
	*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS		*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS

Yoshmd: Created page with "====<48hrs Post Partum==== ''Treatment is targeted against molymicrobial infections'' Clindamycin 900mg q8hrs PLUS Gentamicin 1.5mg/kg IV q8hrs OR Doxycycline 10..."

2015-04-18T15:33:49Z

Created page with "====<48hrs Post Partum==== ''Treatment is targeted against molymicrobial infections'' *Clindamycin 900mg q8hrs PLUS Gentamicin 1.5mg/kg IV q8hrs OR *Doxycycline 10..."

New page

====<48hrs Post Partum====
''Treatment is targeted against molymicrobial infections''
*[[Clindamycin]] 900mg q8hrs PLUS [[Gentamicin]] 1.5mg/kg IV q8hrs OR
*[[Doxycycline]] 100mg IV PO q12hrs daily PLUS
**[[Ampicillin/Sulbactam]] 3g IV q6hrs
**[[Cefoxitin]] 2g IV q6hrs daily

====>48hrs Post Partum====
*[[Doxycycline]] 100mg IV or PO q12hrs + [[Metronidazole]] 500mg IV or PO q8hrs daily

Template:Endometritis Antibiotics - Revision history

Danbot: Convert to AntibioticDose template for SMW integration

Danbot: Convert to AntibioticDose template with disease=Postpartum endometritis for SMW linking

Rossdonaldson1: /* >48hrs Post Partum */

Rossdonaldson1: /* >48hrs Post Partum */

Rossdonaldson1: /* <48hrs Post Partum */

Jsenvisky: /* >48hrs Post Partum */

Kxl328 at 15:31, 17 August 2015

Yoshmd: Created page with "====<48hrs Post Partum==== ''Treatment is targeted against molymicrobial infections'' *Clindamycin 900mg q8hrs PLUS Gentamicin 1.5mg/kg IV q8hrs OR *Doxycycline 10..."

Yoshmd: Created page with "====<48hrs Post Partum==== ''Treatment is targeted against molymicrobial infections'' Clindamycin 900mg q8hrs PLUS Gentamicin 1.5mg/kg IV q8hrs OR Doxycycline 10..."