Trazodone toxicity - Revision history

ClaireLewis at 01:23, 14 September 2019

2019-09-14T01:23:23Z

← Older revision		Revision as of 01:23, 14 September 2019
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	==Clinical Features==		==Clinical Features==
	*CNS depression		*[[CNS Depression\|CNS depression]]
	**Most common symptom		**Most common symptom
	**Rarely produces coma or seizures when it is the only drug ingested		**Rarely produces [[coma]] or [[seizures]] when it is the only drug ingested
	*Respiratory ~~depresion~~		*[[Respiratory distress\|Respiratory depression]]
	**Fairly common (but only with coingestants)		**Fairly common (but only with coingestants)
	*Orthostatic hypotension		*Orthostatic [[hypotension]]
	*QT prolongation		*[[QT prolongation]]

	==Differential Diagnosis==		==Differential Diagnosis==
			{{Sedatve/hypnotic toxicity types}}

	==Evaluation==		==Evaluation==
			*Clinical diagnosis, assess for alternate etiologies

	==Management==		==Management==

2019-09-01T14:40:15Z

Management

← Older revision		Revision as of 14:40, 1 September 2019
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	==Management==		==Management==
	*~~GI decontamination~~		*Supportive care
	**[[Activated charcoal]] x1		*[[Activated charcoal]] and [[gastric lavage]] are not indicated
	**[[~~Gastric~~ lavage]] ~~(consider for coingestants)~~
	*[[QT prolongation]]		*[[QT prolongation]]
	**Treat [[torsades]] in usual manner		**Treat [[torsades]] in usual manner

2017-07-24T01:13:09Z

Text replacement - "alpha" to "α"

← Older revision		Revision as of 01:13, 24 July 2017
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	==Background==		==Background==
	*[[Trazodone]] is extremely safe in overdose as long as there are no coingestants		*[[Trazodone]] is extremely safe in overdose as long as there are no coingestants
	*Has serotonergic and ~~alpha~~ blocking effects		*Has serotonergic and α blocking effects

	==Clinical Features==		==Clinical Features==

2017-07-19T12:22:01Z

Text replacement - "==References== " to "==References== <references/> "

2016-10-05T09:31:19Z

Background

← Older revision		Revision as of 09:31, 5 October 2016
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	==Background==		==Background==
	*[[Trazodone]] is ~~xtremely~~ safe in overdose as long as there are no coingestants		*[[Trazodone]] is extremely safe in overdose as long as there are no coingestants
	*Has serotonergic and alpha blocking effects		*Has serotonergic and alpha blocking effects

2016-10-05T09:31:08Z

Background

← Older revision		Revision as of 09:31, 5 October 2016
Line 1:		Line 1:
	==Background==		==Background==
	*~~Extremely~~ safe in overdose as long as there are no coingestants		*[[Trazodone]] is xtremely safe in overdose as long as there are no coingestants
	*Has serotonergic and alpha blocking effects		*Has serotonergic and alpha blocking effects

2016-07-26T10:00:22Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-09T23:44:19Z

Text replacement - "==Treatment==" to "==Management=="

2016-03-22T16:23:04Z

Text replacement - "Category:Tox" to "Category:Toxicology"

2015-06-03T09:46:48Z

← Older revision		Revision as of 09:46, 3 June 2015
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	==Clinical Features==		==Clinical Features==
	#CNS depression		*CNS depression
	##Most common symptom		**Most common symptom
	##Rarely produces coma or seizures when it is the only drug ingested		**Rarely produces coma or seizures when it is the only drug ingested
	#Respiratory depresion		*Respiratory depresion
	##Fairly common (but only with coingestants)		**Fairly common (but only with coingestants)
	#Orthostatic hypotension		*Orthostatic hypotension
	#QT prolongation		*QT prolongation

			==Differential Diagnosis==

			==Diagnosis==

	==Treatment==		==Treatment==
	#GI decontamination		*GI decontamination
	##Activated charcoal x1		**[[Activated charcoal]] x1
	##Gastric lavage (consider for coingestants)		**[[Gastric lavage]] (consider for coingestants)
	#QT prolongation		*[[QT prolongation]]
	##Treat torsades in usual manner		**Treat [[torsades]] in usual manner
	#Hypotension		*Hypotension
	##IVF		**[[IVF]]
	##Norepinephrine		**[[Norepinephrine]]
	~~###~~Dopamine is contraindicated		***[[Dopamine]] is contraindicated

	==Disposition==		==Disposition==
	*Consider discharge for ~~pts~~ who remain asymptomatic for at least ~~6hr~~		*Consider discharge for patients who remain asymptomatic for at least 6 hours

			==See Also==

	==~~Source~~==		==References==
	*Tintinalli

	[[Category:Tox]]		[[Category:Tox]]