Hodgkin's lymphoma: Difference between revisions
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==Background== | ==Background== | ||
*Spreads from source lymph node to adjacent nodes | *Spreads from source lymph node to adjacent nodes | ||
*Related to viral infections | *Related to viral infections | ||
*More common in males | *More common in males | ||
*Bimodal distribution: young adulthood and older aged | *Bimodal distribution: young adulthood and older aged | ||
Revision as of 01:00, 6 December 2016
Background
- Spreads from source lymph node to adjacent nodes
- Related to viral infections
- More common in males
- Bimodal distribution: young adulthood and older aged
- Most common malignancy between ages of 15-19 yo
- Survival >90% in low-risk patients
Clinical Features
- Painless, firm, lymph node (usually cervical or supraclavicular)
- "B" symptoms: fever, night sweats, wt loss
Differential Diagnosis
Cervical Lymphadenopathy
- Hodgkin's lymphoma
- Non-Hodgkin's lymphoma
- Mononucleosis
- Toxoplasmosis
- Branchial cleft lesions
- Cat scratch disease
- Mycobacterial adenitis
Acute Leukemia/Lymphoma
Evaluation
- CXR
- CT neck/C/A/P
- LN biopsy
Management
- Manage acute complications
- Superior vena cava syndrome
- Upper airway compression
- Do NOT give steroids