Hodgkin's lymphoma: Difference between revisions
No edit summary |
No edit summary |
||
| Line 20: | Line 20: | ||
*CT neck/C/A/P | *CT neck/C/A/P | ||
*LN biopsy | *LN biopsy | ||
**Reed-Sternberg cells next to normal lymphocytes | |||
==Management== | ==Management== | ||
Revision as of 01:02, 6 December 2016
Background
- Spreads from source lymph node to adjacent nodes
- Related to viral infections
- More common in males
- Bimodal distribution: young adulthood and older aged
- Most common malignancy between ages of 15-19 yo
- Survival >90% in low-risk patients
Clinical Features
- Painless, firm, lymph node (usually cervical or supraclavicular)
- "B" symptoms: fever, night sweats, wt loss
Differential Diagnosis
Cervical Lymphadenopathy
- Hodgkin's lymphoma
- Non-Hodgkin's lymphoma
- Mononucleosis
- Toxoplasmosis
- Branchial cleft lesions
- Cat scratch disease
- Mycobacterial adenitis
Acute Leukemia/Lymphoma
Evaluation
- CXR
- CT neck/C/A/P
- LN biopsy
- Reed-Sternberg cells next to normal lymphocytes
Management
- Manage acute complications
- Superior vena cava syndrome
- Upper airway compression
- Do NOT give steroids