Dicyclomine: Difference between revisions

(Created page with "==General== *Type: antispasmodic, antimuscarinic *Indication: traditionally for treatment of irritable bowel syndrome *Dosage Forms: PO, IM **DO NOT GIVE IV *Common Trade Name...")
 
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*Excretion: Urine ~80%, ~10% feces
*Excretion: Urine ~80%, ~10% feces
*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not
*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not
 
==Sources==
*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS  / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.
[[Category:Pharmacology]]
[[Category:Pharmacology]]

Revision as of 13:45, 24 December 2016

General

  • Type: antispasmodic, antimuscarinic
  • Indication: traditionally for treatment of irritable bowel syndrome
  • Dosage Forms: PO, IM
    • DO NOT GIVE IV
  • Common Trade Names: Bentyl®

Adult Dosing

  • 10-20 mg PO or IM q6 prn

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Pharmacology

  • Half-life: ~2 hours
  • Excretion: Urine ~80%, ~10% feces
  • Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which atropine does not

Sources