Dicyclomine: Difference between revisions
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*Excretion: Urine ~80%, ~10% feces | *Excretion: Urine ~80%, ~10% feces | ||
*Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not | *Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which [[atropine]] does not | ||
==Sources== | |||
*McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_. | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
Revision as of 13:45, 24 December 2016
General
- Type: antispasmodic, antimuscarinic
- Indication: traditionally for treatment of irritable bowel syndrome
- Dosage Forms: PO, IM
- DO NOT GIVE IV
- Common Trade Names: Bentyl®
Adult Dosing
- 10-20 mg PO or IM q6 prn
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Pharmacology
- Half-life: ~2 hours
- Excretion: Urine ~80%, ~10% feces
- Mechanism of Action: antimuscarinic, direct smooth muscle antagonism of bradykinin and histamine-induced muscular spasms, which atropine does not
Sources
- McAuley DF. GlobarlRPh Inc. ANTISPASMOTICS - Bowel spasm / cramping / IBS / Hypermotility. Last updated 12/04/2016. http://www.globalrph.com/antispasmotic.htm#Dicyclomine_.
