Propofol: Difference between revisions
(Created page with "==Background== -an ultrashort-acting sedative alkylphenol derivative that induces deep sedation -rapid onset (90-100 seconds) and short duration (2-8 minute half-life) ==C...") |
No edit summary |
||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
#an ultrashort-acting sedative alkylphenol derivative that induces deep sedation | |||
#rapid onset (90-100 seconds) and short duration (2-8 minute half-life) | |||
==Contraindications== | ==Contraindications== | ||
#allergy to soy or eggs | |||
#hypotension | |||
#aortic stenosis | |||
===Higher Risk=== | |||
#Patients >55 years old | |||
#Debilitated patients | |||
#Patients with significant underlying illness (i.e. ASA physical status score III or IV) | |||
^Optimize volume status before administration | |||
Higher | |||
==Side Effects== | ==Side Effects== | ||
#Respiratory depression | |||
#Transient hypotension | |||
#Pain at injection site (inject lidocaine IV first) | |||
==Dose== | ==Dose== | ||
#induction = 1mg/kg IV, followed by 0.5mg/kg every 2-3 minutes as needed | |||
#Small incremental doses (10-30mg) can slowly be administered to effect | |||
===Adjunctive medications=== | |||
#fentanyl or morphine (propofol does not provide analgesia) | |||
#NS for transient hypotension | |||
#Lidocaine flush (to reduce injection pain) | |||
Adjunctive medications | |||
==Pediatric Population== | ==Pediatric Population== | ||
#Safe for procedural sedation in pediatric patients. Same dosing. | |||
Safe for procedural sedation in pediatric patients. Same dosing. | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 04:44, 13 March 2011
Background
- an ultrashort-acting sedative alkylphenol derivative that induces deep sedation
- rapid onset (90-100 seconds) and short duration (2-8 minute half-life)
Contraindications
- allergy to soy or eggs
- hypotension
- aortic stenosis
Higher Risk
- Patients >55 years old
- Debilitated patients
- Patients with significant underlying illness (i.e. ASA physical status score III or IV)
^Optimize volume status before administration
Side Effects
- Respiratory depression
- Transient hypotension
- Pain at injection site (inject lidocaine IV first)
Dose
- induction = 1mg/kg IV, followed by 0.5mg/kg every 2-3 minutes as needed
- Small incremental doses (10-30mg) can slowly be administered to effect
Adjunctive medications
- fentanyl or morphine (propofol does not provide analgesia)
- NS for transient hypotension
- Lidocaine flush (to reduce injection pain)
Pediatric Population
- Safe for procedural sedation in pediatric patients. Same dosing.