Mesenteric panniculitis: Difference between revisions
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==Background== | ==Background== | ||
*Also known as | *Also known as sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery<ref name="Issa">Issa I and Baydoun H. Mesenteric panniculitis: Various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14; 15(30): 3827–3830.</ref> | ||
*A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)<ref name="Issa" />. | |||
*Occurs independently (specific cause unknown) or in association with other disorders<ref name="Issa" /> | |||
==Clinical Features== | ==Clinical Features== | ||
*[[Abdominal pain]] | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
==Evaluation== | ==Evaluation== | ||
*Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”) | *Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”) | ||
**May be confirmed by surgical biopsy | |||
==Management== | ==Management== | ||
*Supportive ED treatment | |||
There is no standardized treatment, and it may consist of anti-inflammatory or immunosuppressive agents. We recommend resection only when the advanced inflammatory changes become irreversible or in cases of bowel obstruction | |||
*Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine) | |||
==Disposition== | ==Disposition== | ||
*Outpatient | |||
==Prognosis== | |||
*Overall prognosis is usually good and recurrence seems to be rare<ref name="Issa" /> | |||
==See Also== | ==See Also== | ||
==External Links== | ==External Links== | ||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:GI]] | |||
Revision as of 18:05, 27 June 2017
Background
- Also known as sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery[1]
- A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)[1].
- Occurs independently (specific cause unknown) or in association with other disorders[1]
Clinical Features
Differential Diagnosis
Evaluation
- Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”)
- May be confirmed by surgical biopsy
Management
- Supportive ED treatment
There is no standardized treatment, and it may consist of anti-inflammatory or immunosuppressive agents. We recommend resection only when the advanced inflammatory changes become irreversible or in cases of bowel obstruction
- Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine)
Disposition
- Outpatient
Prognosis
- Overall prognosis is usually good and recurrence seems to be rare[1]