Rho(D) immune globulin: Difference between revisions

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==Treatment==
==Treatment==
#1st Trimester
#1st Trimester (through 12weeks)
##--> give 50 microgm
##--> give 50 microgm
###(although there is no harm in giving the standard 300 microgram dose, which is more readily available)
#2nd & 3rd Trimester
#2nd & 3rd Trimester
##--> give 300 microgm once and send Kleihauer-Betke test
##--> give 300 microgm once and send Kleihauer-Betke test
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==See Also==
==See Also==
[[Vaginal Bleeding (Main)]]
[[Vaginal Bleeding (Main)]]
==Source==
UpToDate


[[Category:Drugs]]
[[Category:Drugs]]
[[Category:OB/GYN]]
[[Category:OB/GYN]]

Revision as of 08:36, 26 November 2013

Background

  • For fetal maternal hemorrhage
  • Risk = >4-12wks

Treatment

  1. 1st Trimester (through 12weeks)
    1. --> give 50 microgm
      1. (although there is no harm in giving the standard 300 microgram dose, which is more readily available)
  2. 2nd & 3rd Trimester
    1. --> give 300 microgm once and send Kleihauer-Betke test
    2. --> within 72hrs give additional 300 microgm/15 ml Rh-positive blood

Exceptions

  1. Prior sensitization of mother
  2. Known Rh-negative father
  3. Known Rh-negative fetus (from cord blood)

See Also

Vaginal Bleeding (Main)

Source

UpToDate