Rho(D) immune globulin: Difference between revisions
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==Treatment== | ==Treatment== | ||
#1st Trimester (through 12weeks) | #1st Trimester (through 12weeks) | ||
##--> give 50 microgm | ##--> give 50 microgm IM | ||
###(although there is no harm in giving the standard 300 microgram dose, which is more readily available) | ###(although there is no harm in giving the standard 300 microgram dose, which is more readily available) | ||
#2nd & 3rd Trimester | #2nd & 3rd Trimester | ||
##--> give 300 microgm once and send Kleihauer-Betke test | ##--> give 300 microgm IM once and send Kleihauer-Betke test | ||
##--> within 72hrs give additional 300 microgm/15 ml Rh-positive blood | ##--> within 72hrs give additional 300 microgm/15 ml Rh-positive blood | ||
Revision as of 08:37, 26 November 2013
Background
- For fetal maternal hemorrhage
- Risk = >4-12wks
Treatment
- 1st Trimester (through 12weeks)
- --> give 50 microgm IM
- (although there is no harm in giving the standard 300 microgram dose, which is more readily available)
- --> give 50 microgm IM
- 2nd & 3rd Trimester
- --> give 300 microgm IM once and send Kleihauer-Betke test
- --> within 72hrs give additional 300 microgm/15 ml Rh-positive blood
Exceptions
- Prior sensitization of mother
- Known Rh-negative father
- Known Rh-negative fetus (from cord blood)
See Also
Source
UpToDate