Vasopressin: Difference between revisions
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==Pediatric Dosing== | ==Pediatric Dosing== | ||
0.0002–0.008 U/kg/min have been studied although no current consensus on dosage | |||
<ref>https://pdfs.semanticscholar.org/9f71/beefc10500d2d3a14d338d7b86b076729d3b.pdf </ref> | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 19:02, 11 July 2017
General
- Type: Vasopressors
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Dosing
- 0.04 units/min
Rate of Titration
- Fixed dose (do not titrate)
Pediatric Dosing
0.0002–0.008 U/kg/min have been studied although no current consensus on dosage
[1]
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- Bradycardia
- Limb ischemia
- Myocardial ischemia
- Splanchnic ischemia
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Primary Receptor
- V1
Relative Effects
- ↑SVR
- ↓HR
Notes
- Adverse effects are dose-dependent
- Acts on V1 receptors leading to ↑vasoconstriction and
↑sensitivity to catecholamines in patients with shock
Indication
- Adjunct for septic shock