Alpha blockers: Difference between revisions
Neil.m.young (talk | contribs) (Text replacement - "beta blocker" to "β-blocker") |
Neil.m.young (talk | contribs) (Text replacement - "α 2" to "α<sub>2</sub>") |
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*[[Silodosin]] | *[[Silodosin]] | ||
===Selective α 2=== | ===Selective α<sub>2</sub>=== | ||
*[[Atipamezole]] | *[[Atipamezole]] | ||
*[[Idazoxan]] | *[[Idazoxan]] | ||
Revision as of 18:06, 11 August 2017
Background
- Also known as α-blockers
- &α;1-blockers act on &α;1-adrenoceptors
- &α;2-blockers act on &α;2-adrenoceptors
- Act as neutral antagonists or inverse agonists of &α;-adrenergic receptors (α-adrenoceptors)
Medications
Non-selective
- Phenoxybenzamine
- Phentolamine
- Tolazoline
- Trazodone
- Typical and atypical antipsychotics
Selective α 1
Selective α2
Mixed
- The agents carvedilol and labetalol are both α- and β-blockers.
Uses
- hypertension
- Raynaud's disease
- scleroderma
- generalized anxiety disorder
- panic disorder
- posttraumatic stress disorder
- benign prostatic hyperplasia