Numbness: Difference between revisions
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| '''Nerve'''||Unilateral or bilateral||Possible||Yes | | '''Nerve'''||Unilateral or bilateral||Possible||Yes | ||
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| align="center" style="background:#f0f0f0;"|'''Cause''' | |||
| align="center" style="background:#f0f0f0;"|'''Acute (Days)''' | |||
| align="center" style="background:#f0f0f0;"|'''Chronic (Weeks-Months)''' | |||
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| Immune||Guillain-Barre & variants, vasculitis||Chronic demylinating neuropathy | |||
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| Toxins||Botulism, buckthorn, diphtheria, tick, arsenic, organophosphates, thallium, vacor||Heavy metals, environmental chemicals | |||
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| Drugs||Captopril, gangliosides, gold, nitrofurantoin, suramin, zimeldine||chemotheraputic agents | |||
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| Metabolic||Porphyria||Porphyria, diabetes | |||
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| Nutritional||||Vitamin toxicity or deficiency | |||
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| Hereditary||||Hereditary motor and sensory neuropothy, hereditary sensory neuropathy | |||
|} | |} | ||
Revision as of 18:36, 12 August 2017
Background
Clinical Features
Localizing the problem by history & physical[1]
- Distribution of symptoms
- Right vs. left
- Presence of facial involvement
- Arm vs. leg
- Proximal vs. distal
- Symmetric vs. asymmetric
- Characteristics of symptoms
- Sensory and motor
- Painless or Painful
- Sensory only
- Autonomic involvement
- Temporal Features
- Acute or Chronic
- Static or Progressive
Differential Diagnosis
Evaluation
| Region | Distribution | Facial Involvement | Pain |
| Brain | Unilateral | Often | No |
| Spinal cord | Bilateral | No | Possible |
| Nerve root | Unilateral | No | Yes |
| Nerve | Unilateral or bilateral | Possible | Yes |
| Cause | Acute (Days) | Chronic (Weeks-Months) |
| Immune | Guillain-Barre & variants, vasculitis | Chronic demylinating neuropathy |
| Toxins | Botulism, buckthorn, diphtheria, tick, arsenic, organophosphates, thallium, vacor | Heavy metals, environmental chemicals |
| Drugs | Captopril, gangliosides, gold, nitrofurantoin, suramin, zimeldine | chemotheraputic agents |
| Metabolic | Porphyria | Porphyria, diabetes |
| Nutritional | Vitamin toxicity or deficiency | |
| Hereditary | Hereditary motor and sensory neuropothy, hereditary sensory neuropathy |
Management
Disposition
See Also
External Links
References
- ↑ Rosenfeld J, Martin RA, Bauer DW. "Chapter Three - Numbness: A Practical Guide for Family Physicians." American Academy of Neurology. https://www.aan.com/uploadedFiles/Website_Library_Assets/Documents/4.CME_and_Training/2.Training/4.Clerkship_and_Course_Director_Resources/FM_Chp3.pdf