Vancomycin: Difference between revisions
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==General== | ==General== | ||
*Type: | *Type: 125mg, 250mg | ||
*Dosage Forms: | *Dosage Forms: | ||
*Common Trade Names: | **IV | ||
**May mix IV with 30mL water and give PO | |||
**May mix with 100mL NS and give PR | |||
*Common Trade Names: Vancocin | |||
==Adult Dosing== | ==Adult Dosing== | ||
===General=== | |||
*'''<50kg:''' 500mg IV q12h | |||
*'''50-69kg:''' 750mg IV q12h | |||
*'''>70kg:''' 1000mg IV q12h | |||
*Alternative (All Weights): 10-15 mg/kg IV q12 | |||
*Adjust dose based on serum levels | |||
===[[C. Difficile]] Infection=== | |||
*1st occurrence | |||
**Uncomplicated: 125mg PO q6h x 10-14 days | |||
**Complicated: 500mg PO/NG q6h | |||
***May use in combo with metronidazole IV | |||
***Consider adding vancomycin 500mg PR q6 if complete ileus | |||
*2nd occurrence | |||
**Uncomplicated: 125mg PO q6h x 10-14 days | |||
**Complicated: 500mg PO/NG q6h | |||
***May use in combo with metronidazole IV | |||
***Consider adding vancomycin 500mg PR q6 if complete ileus | |||
*3rd+ occurrence | |||
**125mg PO q6h x 10-14 days, then daily x 7 days, then q2-3 days x 2-8 wk | |||
===Staphylococcal Enterocolitis=== | |||
*500-2000 mg/day PO divided q6-8h x 7-10 days | |||
*First Dose: 500mg PO x 1 | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 23:06, 27 February 2014
General
- Type: 125mg, 250mg
- Dosage Forms:
- IV
- May mix IV with 30mL water and give PO
- May mix with 100mL NS and give PR
- Common Trade Names: Vancocin
Adult Dosing
General
- <50kg: 500mg IV q12h
- 50-69kg: 750mg IV q12h
- >70kg: 1000mg IV q12h
- Alternative (All Weights): 10-15 mg/kg IV q12
- Adjust dose based on serum levels
C. Difficile Infection
- 1st occurrence
- Uncomplicated: 125mg PO q6h x 10-14 days
- Complicated: 500mg PO/NG q6h
- May use in combo with metronidazole IV
- Consider adding vancomycin 500mg PR q6 if complete ileus
- 2nd occurrence
- Uncomplicated: 125mg PO q6h x 10-14 days
- Complicated: 500mg PO/NG q6h
- May use in combo with metronidazole IV
- Consider adding vancomycin 500mg PR q6 if complete ileus
- 3rd+ occurrence
- 125mg PO q6h x 10-14 days, then daily x 7 days, then q2-3 days x 2-8 wk
Staphylococcal Enterocolitis
- 500-2000 mg/day PO divided q6-8h x 7-10 days
- First Dose: 500mg PO x 1
Pediatric Dosing
Special Populations
- Pregnancy:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Source
- Epocrates