ITP in Pregnancy: Difference between revisions
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==Background== | ==Background== | ||
# marked diff btwn maternal and fetal platelet counts | |||
# no antenatal measures predict fetal status | |||
# maternal response to medicine does not guarantee a favorable outcome for baby | |||
# only previous neonatal outcomes provide predictor of neonatal platelet counts. | |||
==DDx== | ==DDx== | ||
(low platelets during pregnancy) | (low platelets during pregnancy) | ||
#preg induced HTN | |||
#HELLP | |||
#microangiopathic hemolytic anemia | |||
#hereditary | |||
#thrombocytopenias | |||
==Diagnosis== | ==Diagnosis== | ||
# usually mild thrombocytopenia (>70k) and | |||
# platelet count normalizes p delivery | |||
==Treatment== | ==Treatment== | ||
# most meds teratogenic or with pred- worsens gest diabtetes- so use iv ig mostly | |||
# baby with v low risk of ICH- but higher of normal baby. | |||
# risk of ICH not change with cesarean | |||
# if baby with platelets <30k, try iv ig and or prednisone | |||
iv ig mostly | # exchange xfusion only if severe. | ||
# no problem for breast feeding. | |||
==See Also== | ==See Also== | ||
HEME: ITP | HEME: ITP | ||
==Source== | ==Source== | ||
Revision as of 23:44, 28 March 2011
Background
- marked diff btwn maternal and fetal platelet counts
- no antenatal measures predict fetal status
- maternal response to medicine does not guarantee a favorable outcome for baby
- only previous neonatal outcomes provide predictor of neonatal platelet counts.
DDx
(low platelets during pregnancy)
- preg induced HTN
- HELLP
- microangiopathic hemolytic anemia
- hereditary
- thrombocytopenias
Diagnosis
- usually mild thrombocytopenia (>70k) and
- platelet count normalizes p delivery
Treatment
- most meds teratogenic or with pred- worsens gest diabtetes- so use iv ig mostly
- baby with v low risk of ICH- but higher of normal baby.
- risk of ICH not change with cesarean
- if baby with platelets <30k, try iv ig and or prednisone
- exchange xfusion only if severe.
- no problem for breast feeding.
See Also
HEME: ITP
Source
6/06 MISTRY