P450: Difference between revisions

Latest revision as of 01:28, 27 January 2019

Authors:

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 ==Background==
-Coumadin
+[[Coumadin]]
-==Avoid / P450 Inhibitors==
+==Antimicrobials==
-#Quinolones, esp levoflox
+===Avoid /[[P450]] Inhibitors===
-#Macrolides, esp erythromycin
+*[[Quinolones]], especially [[levofloxacin]]
-#[[Bactrim]] and sulfonamides
+*[[Macrolides]], especially [[erythromycin]]
-#Flagyl
+*[[Bactrim]] and sulfonamides
-#Nafcillin, oxacillin
+*[[Flagyl]]
+*[[Nafcillin]], [[oxacillin]]
-==Use==
+===Use===
-#Azithro
+*[[Azithromycin]]
-#Gentamicin
+*[[Gentamicin]]
-#Cephalosporin, aminopenicillins
+*[[Cephalosporin]], [[aminopenicillins]]
-#Nitrofurantoin
+*[[Nitrofurantoin]]
-#Clinda
+*[[Clindamycin]]
-#Vanc
+*[[Vancomycin]]
+==Significant [[P450]] Inhibitors in General==
+*Grapefruit juice
+*[[Valproate]]]
+*[[INH]]
+*Protease inhibitors (-navir, i.e. ritonavir)
+*[[SSRIs]], except escitalopram
+*[[Amiodarone]]
+*[[Fluoroquinolones]]
+*[[Sulfonamides]]
+*[[Macrolides]]
+*[[Cimetidine]]
+*[[Omeprazole]]
+*[[Ketoconazole]]
+*Acute [[ETOH]]
+==Significant [[P450]] Inducers in General==
+*[[Phenytoin]]
+*[[Carbamazepine]]
+*[[Ethosuximide]]
+*[[Quinidine]]/[[quinine]]
+*[[Rifampin]]
+*[[Griseofulvin]]
+*[[Glucocorticoids]]
+*[[Barbiturates]]
+*St. John's wort
+*Chronic EtOH
+*[[Tobacco]] smoking
+[[Category:Pharmacology]]
-[[Category:Drugs]]