Thrombolytics: Difference between revisions
| Line 28: | Line 28: | ||
*Active peptic ulcer disease | *Active peptic ulcer disease | ||
*Other medical conditions likely to increase risk of bleeding (diabetic retinopathy, etc) | *Other medical conditions likely to increase risk of bleeding (diabetic retinopathy, etc) | ||
==See Also== | ==See Also== | ||
Revision as of 06:48, 5 March 2019
Indications
- Thrombolytics for acute ischemic stroke
- Thrombolytics for pulmonary embolism
- Thrombolytics for STEMI
Thrombolysis contraindications
Absolute contraindication
- Any prior ICH
- Known structural cerebral vascular lesion (AVM)
- Known intracranial neoplasm
- Ischemic stroke within 3 mo
- Active internal bleeding (excluding menses)
- Suspected aortic dissection or pericarditis
Relative contraindications
- Severe uncontrolled BP (>180/110)
- History of chronic severe poorly controlled hypertension
- History of ischemic stroke within past 3 months
- Known intracranial pathology not covered in absolute contraindications
- Current use of anticoagulants with known INR >2–3
- Known bleeding diathesis
- Recent trauma (past 2 wk)
- Prolonged CPR (>10 min)
- Major surgery (<3 wk)
- Noncompressible vascular punctures (e.g. subclavian) within past 7 days
- Recent internal bleeding (within 2–4 wk)
- Patients treated previously with streptokinase should not receive streptokinase again
- Pregnancy
- Active peptic ulcer disease
- Other medical conditions likely to increase risk of bleeding (diabetic retinopathy, etc)