Chlamydophila psittaci: Difference between revisions

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==Background==
==Background==
*6 avian serovars (A-F) and 2 mammalian isolates (WC and M56)
*6 avian serovars (A-F) and 2 mammalian isolates (WC and M56)
*Reservoirs: birds, duck, geese, turkeys, cattle, muskrats
*Reservoirs: birds (465 species), duck, geese, turkeys, cattle, muskrats
*Transmission: inhalation from aerosolized urine, feces, dried feces, eye secretions. Person-to-person transmission is possible but rare.
*Incubation period usually 5-14 days but can be up to 1 month
*Incubation period usually 5-14 days but can be up to 1 month
*All transmittable to humans with potential for severe disease  
*All transmittable to humans with potential for severe disease  

Revision as of 01:28, 4 June 2014

Background

  • 6 avian serovars (A-F) and 2 mammalian isolates (WC and M56)
  • Reservoirs: birds (465 species), duck, geese, turkeys, cattle, muskrats
  • Transmission: inhalation from aerosolized urine, feces, dried feces, eye secretions. Person-to-person transmission is possible but rare.
  • Incubation period usually 5-14 days but can be up to 1 month
  • All transmittable to humans with potential for severe disease

Clinical Features

  • Contact with above birds/animals
  • High fever (up to 40.5C)
  • Common: Low pulse, chills, headache, myalgia, nonproductive cough
  • Less common: vomiting, abdominal pain, diarrhea, trace hemoptysis
  • Complications: myocarditis, endocarditis, icterus, encephalitis, ARDS, MODs

Differential Diagnosis

Workup

  • CBC-leukopenia in 25% of cases
  • Chemistry
  • CRP
  • LFT
  • CXR-usually lower lobe consolidation
  • Sputum culture

Management

  • Doxycycline 100mg PO Q12h x 10-14 days or
  • Azithromycin 500mg PO Qday x 7 days

Disposition

Home if no complications

Sources

  • Beeckman, Zoonotic Chlamydophila psittaci infections from a clinical perspective. Clinical Microbiology and Infection, (2009) 15:11-17.
  • Tintinalli