Lansoprazole: Difference between revisions
ClaireLewis (talk | contribs) (Created page with "==Administration== *Type: PPI *Dosage Forms: *Routes of Administration: oral, IV *Common Trade Names: Prevacid ==Adult Dosing== *15-30mg daily ==Pediatric Dosing== *Age...") |
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==Administration== | ==Administration== | ||
*Type: [[PPI]] | *Type: [[PPI]] | ||
*Dosage Forms: | *Dosage Forms: Capsule and Tablet; 15mg & 30mg | ||
*Routes of Administration: oral, IV | *Routes of Administration: oral, IV | ||
*Common Trade Names: Prevacid | *Common Trade Names: Prevacid | ||
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<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:GI]] | |||
Latest revision as of 22:50, 22 September 2019
Administration
- Type: PPI
- Dosage Forms: Capsule and Tablet; 15mg & 30mg
- Routes of Administration: oral, IV
- Common Trade Names: Prevacid
Adult Dosing
- 15-30mg daily
Pediatric Dosing
- Age 1-11 years, weight <30kg: 15mg daily
- Age >1 year, weight >30kg: 15-30mg daily
Special Populations
- Pregnancy Rating: B
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing: no adjustment
- Hepatic dosing: if severe, consider dose reduction
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- C. difficile diarrhea
- SJS/TEN
- Rhabdomyolysis
- Interstitial nephritis
- Fracture
- Hypomagnesemia
Common
- Abdominal pain, diarrhea, nausea, constipation
- Headache
Pharmacology
- Half-life: 1.5-3 hours
- Metabolism: Hepatic
- Excretion: Mostly biliary/fecal
Mechanism of Action
- Inhibits gastric parietal cell H+/K+ proton pump, leading to decreased gastric acid secretion