Template:Acute cystitis antibiotics: Difference between revisions
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*[[Ciprofloxacin]] 400mg IV q12hr, OR | *[[Ciprofloxacin]] 400mg IV q12hr, OR | ||
*[[Ceftriaxone]] 1gm IV QD, OR | *[[Ceftriaxone]] 1gm IV QD, OR | ||
*Cefotaxime 1-2gm IV q8hr, OR | *[[Cefotaxime]] 1-2gm IV q8hr, OR | ||
*[[Gentamicin]] 3mg/kg/day divided q8hr +/- ampicillin 1–2 gm q4hr, OR | *[[Gentamicin]] 3mg/kg/day divided q8hr +/- ampicillin 1–2 gm q4hr, OR | ||
*[[Piperacillin/Tazobactam]] 3.375 gm IV q6hr, OR | *[[Piperacillin/Tazobactam]] 3.375 gm IV q6hr, OR | ||
*[[Cefepime]] 2gm IV q8hr, OR | *[[Cefepime]] 2gm IV q8hr, OR | ||
*[[Imipenem]] 500mg IV q8hr | *[[Imipenem]] 500mg IV q8hr | ||
Revision as of 17:01, 15 October 2019
Outpatient
Women, Uncomplicated
- Nitrofurantoin ER 100mg BID x 5d, OR
- TMP/SMX DS (160/800mg) 1 tab BID x 3d, OR
- Cephalexin 250mg QID x 5d, OR
- Ciprofloxacin 250mg BID x3d
- Avoid using fluoroquinolone for the first-line treatment of uncomplicated urinary tract infections (UTIs) in women.[1]
- Fosfomycin 3 g PO once
- Lower clinical and microbiologic success compared to nitrofurantoin TID for 5 days [2]
Women, Complicated
- Ciprofloxacin 500mg BID x10-14d, OR
- Cefpodoxime 200 mg BID x10-14d
Women, Concern for Urethritis
- Ceftriaxone 250mg IM x1 AND azithromycin 1gm PO x1 AND nitrofurantoin ER 100mg BID x5d, OR
- Levofloxacin 500mg QD x 14d (covers urinary pathogens, GC, and chlamydia)
- GC resistance to fluoroquinolones is increasing
Men
- Ciprofloxacin 500mg BID x10-14d, OR
- Cefpodoxime 200 mg BID x10-14d
Inpatient Options
- Ciprofloxacin 400mg IV q12hr, OR
- Ceftriaxone 1gm IV QD, OR
- Cefotaxime 1-2gm IV q8hr, OR
- Gentamicin 3mg/kg/day divided q8hr +/- ampicillin 1–2 gm q4hr, OR
- Piperacillin/Tazobactam 3.375 gm IV q6hr, OR
- Cefepime 2gm IV q8hr, OR
- Imipenem 500mg IV q8hr
- ↑ Choosing Wisely. American Urogynecologic Society. http://www.choosingwisely.org/societies/american-urogynecologic-society
- ↑ Huttner, A., Kowalczyk, A., Turjeman, A., Babich, T., Brossier, C., Eliakim-Raz, N., … Harbarth, S. (2018). Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial. JAMA: The Journal of the American Medical Association, 319(17), 1781–1789.