Giant cell tumor: Difference between revisions

(Created page with "==Background== *Benign tumor that is locally aggressive causing osteolytic destruction *Although classified as benign lesions, metastasis does occur in a small percentage of p...")
 
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==Clinical Features==
==Clinical Features==
 
*Pain and edema over a joint near a long bone (usually around the knee)
**Classically in a young female adult
*Can present as a pathological fracture
*Nearly all present with just a single tumor site


==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 22:45, 21 November 2019

Background

  • Benign tumor that is locally aggressive causing osteolytic destruction
  • Although classified as benign lesions, metastasis does occur in a small percentage of patients, typically to lungs
    • These are known as benign pulmonary implants as they do not carry the same poor prognostic implication as lung metastasis from other malignancies
  • 3 to 5 percent of all primary bone tumors
    • Around 20 percent in the Chinese population
  • Increased incidence in patients who have been diagnosed with Paget disease of the bone

Clinical Features

  • Pain and edema over a joint near a long bone (usually around the knee)
    • Classically in a young female adult
  • Can present as a pathological fracture
  • Nearly all present with just a single tumor site

Differential Diagnosis

Evaluation

Management

Disposition

See Also

External Links

References