EBQ:Lactate clearance vs central venous oxygen saturation: Difference between revisions
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==Conclusion== | ==Conclusion== | ||
For patients with septic shock who were treated by normalizing CVP and MAP; attempt to normalize lactate clearance as opposed to normalize SVO2 showed no significant difference in in-hospital mortality. | |||
==Major Points== | ==Major Points== | ||
Revision as of 06:45, 4 November 2014
incomplete Journal Club Article
Jones AE.. "Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial". JAMA. 2010. 303(8):739-746.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Is lactate clearance as good as SVO2 as a measure of oxygen delivery to tissues in patients presenting with severe sepsis and septic shock?
Conclusion
For patients with septic shock who were treated by normalizing CVP and MAP; attempt to normalize lactate clearance as opposed to normalize SVO2 showed no significant difference in in-hospital mortality.