Cardiac enzymes: Difference between revisions

m (Rossdonaldson1 moved page Cardiac Enzymes to Cardiac enzymes)
Line 1: Line 1:
== Markers ==
== Markers ==
 
{{Cardiac enzyme timecourse chart}}
{| cellspacing="1" cellpadding="1" border="1" width="300" class="pbNotSortable"
|-
| '''Name'''
| '''INTL'''
| '''ELV PEAK'''
| '''RETRN'''
|-
| myglbn
| 1-4h
| 6-7h
| 18-24h
|-
| trp I
| 3-12
| 10-24
| 3-10d
|-
| trp T
| 3-12
| 10-24
| 5-14d
|-
| ckmb
| 4-12
| 12-24
| 48-72
|-
| ldh
| 8-12
| 24-48
| 10-14d
|}


<br>  
<br>  

Revision as of 20:30, 2 February 2015

Markers

Template:Cardiac enzyme timecourse chart


  • n I - 2-4 hrs 1st detect
    • 8-12 hrs w/100% sensitivity
    • 10-24 peak
    • 5-10 day duration
  • Tn T - above plus 5-14 d duration
    • CK-MB : 3-4
    • 8-12 (100% sensitive)
    • 10-24 hr peak</font></font></span>
  • MYOGLOBIN : 1-2 hrs detect first
    • 4-8 100% sens
    • 4-8 peak
    • 0.5-1.0 duration
    • 2-4 day duration</font></font></span>

Creatine Phosphokinase

  • can be elevated in trauma, rhabdo, hyperthermia, physical activity, renal or endocrine dz, systemic infections
  • if pt small with small muscle mass to begin with, total ck may not be elevated- so better to use ck index- is ratio of ckmb/ total ck. Elevated if > 3- 5%.
  • CK Mass: with monoclonal antibody techniques, can directly measure ck mb mass as mmcg/L. More sensitive for detection of ami

See Also

Retrieved from "https://www.wikem.org/w/index.php?title=Cardiac_enzymes&oldid=30578"