Neutropenic enterocolitis: Difference between revisions

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==Definition==
==Background==
Necrosis of bowel wall 2/2 microbial invasion
*Necrosis of bowel wall 2/2 polymicrobial invasion
 
**Involves terminal ileum and colon
==Pathophysiology==
**May progress to full-thickness infarction/perforation
#Usually involves the CECUM
*Occurs 10-14d after cytotoxic therapy
#Typically occurs 10-14d after cytotoxic therapy


==Diagnosis==
==Diagnosis==
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#Nausea
#Nausea
#Vomiting
#Vomiting
#(mimics appy)


==Workup==
==Workup==
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==Disposition==
==Disposition==
Surgical consultation (right hemicolectomy)
*Sx consult (poss right hemicolectomy)
 
==Prognosis==
Mortality 50%


[[Category:GI]]
[[Category:GI]]
[[Category:ID]]
[[Category:ID]]

Revision as of 06:49, 30 June 2011

Background

  • Necrosis of bowel wall 2/2 polymicrobial invasion
    • Involves terminal ileum and colon
    • May progress to full-thickness infarction/perforation
  • Occurs 10-14d after cytotoxic therapy

Diagnosis

  1. Fever
  2. RLQ pain
  3. Nausea
  4. Vomiting

Workup

CT A/P: cecal distention and wall thickening

Treatment

  1. Bowel rest
  2. NG suction
  3. IVF
  4. Broad spec abx

Disposition

  • Sx consult (poss right hemicolectomy)