Template:Uncomplicated Diverticulitis Antibiotics: Difference between revisions
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'''Options:''' | '''Options:''' | ||
*[[Metronidazole]] 500mg PO | *[[Metronidazole]] 500mg PO Q8hrs AND [[Ciprofloxacin]] 500mg PO BID x5days | ||
*[[Amoxicillin/Clavulanate]] 875/125 PO BID | *[[Amoxicillin/Clavulanate]] 875/125 PO Q8hrs x5days (or [[Augmentin]] XR 2 tablets BID [each tablet 1gm [[amoxicillin]] 62.5mg clavulanate])<ref>Balasubramanian I et al. Out-Patient Management of Mild or Uncomplicated Diverticulitis: A Systematic Review. Dig Surg. 2017;34(2):151-160.</ref><ref>The STAND trial: Jaung R, Nisbet S, Gosselink MP, Di Re A, Keane C, Lin A, Milne T, Su’a B, Rajaratnam S, Ctercteko G, Hsee L, Rowbotham D, Hill A, Bissett I. Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial. Clin Gastroenterol Hepatol. 2020 Mar 30:S1542-3565(20)30426-2. doi: 10.1016/j.cgh.2020.03.049. PMID: 32240832</ref> | ||
*[[Trimethoprim/Sulfamethoxazole]], one double-strength tablet bid, and [[Metronidazole]] 500 mg | *[[Trimethoprim/Sulfamethoxazole]], one double-strength tablet bid, and [[Metronidazole]] 500 mg Q8h | ||
*[[Moxifloxacin]] 400mg PO QDaily<ref> Wilkins T et al. Diagnosis and Management of Acute Diverticulitis. Am Fam Physician. 2013 May 1;87(9):612-620.</ref> | |||
Latest revision as of 01:57, 31 January 2022
Options:
- Metronidazole 500mg PO Q8hrs AND Ciprofloxacin 500mg PO BID x5days
- Amoxicillin/Clavulanate 875/125 PO Q8hrs x5days (or Augmentin XR 2 tablets BID [each tablet 1gm amoxicillin 62.5mg clavulanate])[1][2]
- Trimethoprim/Sulfamethoxazole, one double-strength tablet bid, and Metronidazole 500 mg Q8h
- Moxifloxacin 400mg PO QDaily[3]
- ↑ Balasubramanian I et al. Out-Patient Management of Mild or Uncomplicated Diverticulitis: A Systematic Review. Dig Surg. 2017;34(2):151-160.
- ↑ The STAND trial: Jaung R, Nisbet S, Gosselink MP, Di Re A, Keane C, Lin A, Milne T, Su’a B, Rajaratnam S, Ctercteko G, Hsee L, Rowbotham D, Hill A, Bissett I. Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial. Clin Gastroenterol Hepatol. 2020 Mar 30:S1542-3565(20)30426-2. doi: 10.1016/j.cgh.2020.03.049. PMID: 32240832
- ↑ Wilkins T et al. Diagnosis and Management of Acute Diverticulitis. Am Fam Physician. 2013 May 1;87(9):612-620.