Template:Antibiotics Open Fracture: Difference between revisions
(Created page with "*NNT 16 to prevent early fracture site infection<ref>TheNNT.com Early Antibiotic Use in Open Fractures http://www.thennt.com/nnt/antibiotics-for-open-fractures/</ref> '''Grade...") |
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*NNT 16 to prevent early fracture site infection<ref>TheNNT.com Early Antibiotic Use in Open Fractures http://www.thennt.com/nnt/antibiotics-for-open-fractures/</ref> | *NNT 16 to prevent early fracture site infection<ref>TheNNT.com Early Antibiotic Use in Open Fractures http://www.thennt.com/nnt/antibiotics-for-open-fractures/</ref> | ||
====Grade I Fracture Options==== | |||
*[[Cefazolin]] (Ancef) 2g IV three times daily | *[[Cefazolin]] (Ancef) 2g IV three times daily | ||
*[[Ciprofloxacin]] 400mg IV BID (avoid in pediatrics) | *[[Ciprofloxacin]] 400mg IV BID (avoid in pediatrics) | ||
====Grade II/III Fracture Options==== | |||
*Add [[Gentamicin]] 300 mg (1-1.7mg/kg) IV to any of the Grade I regemins | *Add [[Gentamicin]] 300 mg (1-1.7mg/kg) IV to any of the Grade I regemins | ||
*If concern for [[Clostridium]] then consider single drug regimen of [[Pipericillin/Tazobactam]] 4.5g (80mg/kg) IV three times daily | *If concern for [[Clostridium]] then consider single drug regimen of [[Pipericillin/Tazobactam]] 4.5g (80mg/kg) IV three times daily | ||
Revision as of 18:37, 6 April 2015
- NNT 16 to prevent early fracture site infection[1]
Grade I Fracture Options
- Cefazolin (Ancef) 2g IV three times daily
- Ciprofloxacin 400mg IV BID (avoid in pediatrics)
Grade II/III Fracture Options
- Add Gentamicin 300 mg (1-1.7mg/kg) IV to any of the Grade I regemins
- If concern for Clostridium then consider single drug regimen of Pipericillin/Tazobactam 4.5g (80mg/kg) IV three times daily
- ↑ TheNNT.com Early Antibiotic Use in Open Fractures http://www.thennt.com/nnt/antibiotics-for-open-fractures/