Acetaminophen: Difference between revisions

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==Adult Dosing==
==Adult Dosing==
===General===
*PO
**Immediate-release
***Regular strength: 650 mg q4-6 hours
***Extra strength: 1000 mg every 6 hours
**Extended-release: 1300 mg every 8 hours
*Rectal: 650 mg every 4 to 6 hours
*IV:
**<50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours  ; maximum single dose: 15 mg/kg/dose (≤750 mg/dose)
**≥50 kg: 650 mg every 4 hours or 1000 mg every 6 hours
*Maximum daily dose: 4g


==Pediatric Dosing==
==Pediatric Dosing==
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===Common===
===Common===
==Warnings==
*When calculating maximum daily dose consider all sources of acetaminophen
*Be careful that the dose in milligrams and milliliters is not confused


==Pharmacology==
==Pharmacology==

Revision as of 20:08, 8 April 2015

General

  • Type:
  • Dosage Forms:
  • Common Trade Names: Tylenol

Adult Dosing

General

  • PO
    • Immediate-release
      • Regular strength: 650 mg q4-6 hours
      • Extra strength: 1000 mg every 6 hours
    • Extended-release: 1300 mg every 8 hours
  • Rectal: 650 mg every 4 to 6 hours
  • IV:
    • <50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours  ; maximum single dose: 15 mg/kg/dose (≤750 mg/dose)
    • ≥50 kg: 650 mg every 4 hours or 1000 mg every 6 hours
  • Maximum daily dose: 4g

Pediatric Dosing

  • 15 mg/kg/dose Q6 hours

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Warnings

  • When calculating maximum daily dose consider all sources of acetaminophen
  • Be careful that the dose in milligrams and milliliters is not confused

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources