Template:Otitis Media Antibiotics: Difference between revisions

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#'''[[Amoxicillin]] 80-90mg/kg/day divided into 2 daily doses x5-7days'''
====Initial Treatment====
#*1st line
''Treatment is targeted at S. pneumoniae, H. influenzae, Moraxella catarrhalis, S. pyogenes, S. aureus, and Rhinovirus''
#'''[[Amoxicillin]] 80-90mg/kg/day divided into 2 daily doses 7-10 days'''
====Treatment during prior Month====
#Can use Amoxicillin as same dosing as initial treatment
#'''[[Cefdinir]]''' 14mg/kg/day BID x7-10 days
#'''[[Cefpodoxime]]''' 10mg/kg PO daily x7-10 days
#'''[[Cefuroxime]]''' 15mg/kg PO BID x7-10 days
#'''[[Cefprozil]]''' 15mg/kg PO BID x7-10 days
====Treatment Failure====
''defined as treatment during the prior 7-10 days''
#'''[[Amoxicillin/Clavulanate]]'''
#'''[[Amoxicillin/Clavulanate]]'''
#*80-90mg of amoxicillin per kg/day
#*80-90mg of amoxicillin per kg/day
#*Consider if symptoms persist >72hr after amox begun
#*Clavulanate increases vomiting/diarrhea  
#*Clavulanate increases vomiting/diarrhea  
#'''[[Ceftriaxone]]''' 50mg/kg IM once as single injection x 3 days
#*Use if cannot tolerate PO
====Penicillin Allergy====
#'''[[Azithromycin]]''' 10mg/kg/day x 1 day and 5mg/kg/day x 4 remaining days
#'''[[Azithromycin]]''' 10mg/kg/day x 1 day and 5mg/kg/day x 4 remaining days
#*Consider if penicillin allergic
#'''[[Clarithromycin]]''' 7.5mg/kg PO BID x 10 days
#'''[[Ceftriaxone]]''' 50mg/kg IM once as single injection
#'''[[Clindamycin]]''' 10mg/kg PO three times daily
#*Use if cannot tolerate PO  
#*Clindamycin does not cover H. influenza and M. catarrhalis and treatment should favor Azithromycin use
#'''[[Cefdinir]]''' 14mg/kg/day BID x 5 days

Revision as of 13:30, 13 April 2015

Initial Treatment

Treatment is targeted at S. pneumoniae, H. influenzae, Moraxella catarrhalis, S. pyogenes, S. aureus, and Rhinovirus

  1. Amoxicillin 80-90mg/kg/day divided into 2 daily doses 7-10 days

Treatment during prior Month

  1. Can use Amoxicillin as same dosing as initial treatment
  2. Cefdinir 14mg/kg/day BID x7-10 days
  3. Cefpodoxime 10mg/kg PO daily x7-10 days
  4. Cefuroxime 15mg/kg PO BID x7-10 days
  5. Cefprozil 15mg/kg PO BID x7-10 days

Treatment Failure

defined as treatment during the prior 7-10 days

  1. Amoxicillin/Clavulanate
    • 80-90mg of amoxicillin per kg/day
    • Clavulanate increases vomiting/diarrhea
  2. Ceftriaxone 50mg/kg IM once as single injection x 3 days
    • Use if cannot tolerate PO

Penicillin Allergy

  1. Azithromycin 10mg/kg/day x 1 day and 5mg/kg/day x 4 remaining days
  2. Clarithromycin 7.5mg/kg PO BID x 10 days
  3. Clindamycin 10mg/kg PO three times daily
    • Clindamycin does not cover H. influenza and M. catarrhalis and treatment should favor Azithromycin use