Platelet transfusion: Difference between revisions
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==General== | ==General== | ||
*Type: | *Type: [[Blood products]] | ||
*Dosage Forms: | *Dosage Forms: | ||
*Common Trade Names: | *Common Trade Names: | ||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 17:52, 29 May 2015
General
- Type: Blood products
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Thrombocytopenia
- 1 unit raises count by 50K
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- Plt count <10K in asymptomatic patients (unless due to ITP, TTP, or HIT)
- Plt count <15K with a coagulation disorder or minor bleeding
- Plt count <20K with major bleeding
- Plt count <50K with need for invasive procedure or surgery
- Plt count <100K with need for neurologic or cardiac surgery
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Comments
- Transfusion should be type specific because platelets are bathed in plasma
- Non-type specific platelets can be used but results in higher rate of complications
- Like pRBCs, platelets can be leukocyte reduced or washed