Template:Antibiotics Ludwigs Immunocompromised: Difference between revisions
(Add pediatric immunocompromised dosing) |
|||
| (7 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
====Immunocompromised<ref>Spitalnic SJ, Sucov A. Ludwig's angina: case report and review. J Emerg Med. 1995;13:499-503</ref>==== | ====Immunocompromised<ref>Spitalnic SJ, Sucov A. Ludwig's angina: case report and review. J Emerg Med. 1995;13:499-503</ref>==== | ||
* | |||
* | *{{AntibioticDose|disease=Ludwig's angina|drug=Cefepime|dose=2 g IV q12 hrs|context=Immunocompromised}} + {{AntibioticDose|disease=Ludwig's angina|drug=Metronidazole|dose=500 mg IV q6 hrs|context=Immunocompromised}} OR | ||
* | *{{AntibioticDose|disease=Ludwig's angina|drug=Meropenem|dose=1 g IV q8 hrs|context=Immunocompromised}} OR | ||
* | *{{AntibioticDose|disease=Ludwig's angina|drug=Imipenem/Cilastatin|dose=500mg (20mg/kg) IV q6 hours|context=Immunocompromised}} | ||
*Add | *{{AntibioticDose|disease=Ludwig's angina|drug=Piperacillin/Tazobactam|dose=4.5g (80mg/kg) IV q6 hours|context=Immunocompromised}} | ||
*Add {{AntibioticDose|disease=Ludwig's angina|drug=Vancomycin|dose=15-20 mg/kg IV q8 hrs (max 2 g per dose)|context=Immunocompromised, MRSA}} if concern for MRSA risk factors | |||
====Pediatric Immunocompromised==== | |||
*{{AntibioticDose|disease=Ludwig's angina|drug=Cefepime|dose=50mg/kg IV q8hrs (max 2g)|context=Pediatric Immunocompromised|population=Pediatric}} + {{AntibioticDose|disease=Ludwig's angina|drug=Metronidazole|dose=7.5mg/kg IV q6hrs (max 500mg)|context=Pediatric Immunocompromised|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Ludwig's angina|drug=Meropenem|dose=20mg/kg IV q8hrs (max 1g)|context=Pediatric Immunocompromised|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Ludwig's angina|drug=Piperacillin/Tazobactam|dose=80-100mg/kg IV q6-8hrs (max 4.5g)|context=Pediatric Immunocompromised|population=Pediatric}} | |||
*Add {{AntibioticDose|disease=Ludwig's angina|drug=Vancomycin|dose=15mg/kg IV q6hrs|context=Pediatric MRSA|population=Pediatric}} if concern for MRSA | |||
Latest revision as of 13:02, 20 March 2026
Immunocompromised[1]
- Cefepime 2 g IV q12 hrs + Metronidazole 500 mg IV q6 hrs OR
- Meropenem 1 g IV q8 hrs OR
- Imipenem/Cilastatin 500mg (20mg/kg) IV q6 hours
- Piperacillin/Tazobactam 4.5g (80mg/kg) IV q6 hours
- Add Vancomycin 15-20 mg/kg IV q8 hrs (max 2 g per dose) if concern for MRSA risk factors
Pediatric Immunocompromised
- Cefepime 50mg/kg IV q8hrs (max 2g) + Metronidazole 7.5mg/kg IV q6hrs (max 500mg) OR
- Meropenem 20mg/kg IV q8hrs (max 1g) OR
- Piperacillin/Tazobactam 80-100mg/kg IV q6-8hrs (max 4.5g)
- Add Vancomycin 15mg/kg IV q6hrs if concern for MRSA
- ↑ Spitalnic SJ, Sucov A. Ludwig's angina: case report and review. J Emerg Med. 1995;13:499-503