Acrylonitrile toxicity: Difference between revisions
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=Background= | ==Background== | ||
*Unique type of [[Cyanide|Cyanide toxicity]] | *Unique type of [[Cyanide|Cyanide toxicity]] | ||
*Used in the production of plastics | *Used in the production of plastics | ||
**'''Structure:''' Nitrile group linked to a Vinyl group | **'''Structure:''' Nitrile group linked to a Vinyl group | ||
=Mechanism of Action= | ===Mechanism of Action=== | ||
*Chemical itself is hepatotoxic | *Chemical itself is hepatotoxic | ||
*Also metabolized to form cyanide molecule | *Also metabolized to form cyanide molecule | ||
=Treatment= | ==Clinical Features== | ||
==Differential Diagnosis== | |||
==Diagnosis== | |||
==Treatment== | |||
*[[Cyanide#Treatment|Cyanide Antidotes]] | *[[Cyanide#Treatment|Cyanide Antidotes]] | ||
*[[N-Acetylcysteine|N-Acetylcysteine]] | *[[N-Acetylcysteine|N-Acetylcysteine]] | ||
== | ==References== | ||
*Haddad and Wincester's Toxicology page 1309 | *Haddad and Wincester's Toxicology page 1309 | ||
*[[Wikipedia:Acrylonitrile|Wikipedia]] | *[[Wikipedia:Acrylonitrile|Wikipedia]] | ||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 12:34, 29 June 2015
Background
- Unique type of Cyanide toxicity
- Used in the production of plastics
- Structure: Nitrile group linked to a Vinyl group
Mechanism of Action
- Chemical itself is hepatotoxic
- Also metabolized to form cyanide molecule
Clinical Features
Differential Diagnosis
Diagnosis
Treatment
References
- Haddad and Wincester's Toxicology page 1309
- Wikipedia