Postpartum endometritis: Difference between revisions
No edit summary |
|||
| Line 17: | Line 17: | ||
#Colonization with [[Group B Strep]] | #Colonization with [[Group B Strep]] | ||
<br /> | |||
==Diagnosis== | ==Diagnosis== | ||
#[[Fever]] | #[[Fever]] | ||
| Line 23: | Line 24: | ||
#Uterine tenderness | #Uterine tenderness | ||
#Only scant discharge may be present (esp w/ group B strep) | #Only scant discharge may be present (esp w/ group B strep) | ||
#Evaluate for retained products of conception | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 15:26, 17 August 2015
Background
- Any postpartum woman with fever should be assumed to have a genital tract infection
Risk Factors
- Cesarean delivery (most important)
- Prolonged labor
- Prolonged ROM
- Internal fetal or uterine monitoring
- Large amount of meconium in amniotic fluid
- Manual removal of placenta
- Diabetes Mellitus
- Preterm birth
- Bacterial vaginosis
- Operative vaginal delivery
- Post-term pregnancy
- HIV infection
- Colonization with Group B Strep
Diagnosis
- Fever
- Foul-smelling lochia
- Leukocytosis
- Uterine tenderness
- Only scant discharge may be present (esp w/ group B strep)
- Evaluate for retained products of conception
Differential Diagnosis
- Respiratory tract infection
- UTI/urosepsis
- Pyelonephritis
- Intra-abdominal abscess
- Thrombophlebitis
3rd Trimester/Postpartum Emergencies
- Acute fatty liver of pregnancy
- Amniotic fluid embolus
- Chorioamnionitis
- Eclampsia
- HELLP syndrome
- Mastitis
- Peripartum cardiomyopathy
- Postpartum endometritis (postpartum PID)
- Postpartum headache
- Postpartum hemorrhage
- Preeclampsia
- Resuscitative hysterotomy
- Retained products of conception
- Septic abortion
- Uterine rupture
Management
Antibiotics
<48hrs Post Partum
Treatment is targeted against polymicrobial infections, most often 2-3 organisms of normal vaginal flora
- (Prefered first line) Clindamycin 900mg q8hrs PLUS Gentamicin 5mg/kg IV q24hours (same efficacy and more cost effective vs. 1.5mg/kg) or 1.5mg/kg IV q8hrs[1] OR
- Doxycycline 100mg IV PO q12hrs daily PLUS
- Ampicillin/Sulbactam 3g IV q6hrs
- Cefoxitin 2g IV q6hrs daily
>48hrs Post Partum
- Doxycycline 100mg IV or PO q12hrs + Metronidazole 500mg IV or PO q8hrs daily
- Use Metronidazole with caution in breastfeeding mothers its active is present in breast milk at concentrations similar to maternal plasma concentrations
Disposition
- Consult OB/GYN first if are considering outpt management
- Admit all pts who appear ill, have had a C-section, or underlying comorbid conditions
See Also
Source
- Tintinalli
- Rosen's
- ↑ Mackeen AD, Packard RE, Ota E, Speer L. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev. 2015 Feb 2;2015(2):CD001067. doi: 10.1002/14651858.CD001067.pub3. PMID: 25922861; PMCID: PMC7050613