Rho(D) immune globulin: Difference between revisions
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==Treatment== | ==Treatment== | ||
*1st Trimester (through 12weeks) | |||
**--> give 50 microgm IM | |||
***(although there is no harm in giving the standard 300 microgram dose, which is more readily available) | |||
*2nd & 3rd Trimester | |||
**--> give 300 microgm IM once and send Kleihauer-Betke test | |||
**--> within 72hrs give additional 300 microgm/15 ml Rh-positive blood | |||
===Exceptions=== | ===Exceptions=== | ||
*Prior sensitization of mother | |||
*Known Rh-negative father | |||
*Known Rh-negative fetus (from cord blood) | |||
==See Also== | ==See Also== | ||
Revision as of 07:10, 29 August 2015
Background
- For fetal maternal hemorrhage
- Risk = >4-12wks
- Also given to Rh- male trauma patients who receive O+ blood to prevent future reaction with O+ transfusions[1]
Treatment
- 1st Trimester (through 12weeks)
- --> give 50 microgm IM
- (although there is no harm in giving the standard 300 microgram dose, which is more readily available)
- --> give 50 microgm IM
- 2nd & 3rd Trimester
- --> give 300 microgm IM once and send Kleihauer-Betke test
- --> within 72hrs give additional 300 microgm/15 ml Rh-positive blood
Exceptions
- Prior sensitization of mother
- Known Rh-negative father
- Known Rh-negative fetus (from cord blood)
See Also
Source
- ↑ Miraflor, E, et al. Emergency uncrossmatched transfusion effect on blood type alloantibodies. J Trauma. 2012; 72:48-53.