P450: Difference between revisions
No edit summary |
|||
| Line 2: | Line 2: | ||
[[Coumadin]] | [[Coumadin]] | ||
==Antimicrobials== | |||
===Avoid / P450 Inhibitors=== | ===Avoid / P450 Inhibitors=== | ||
*[[Quinolones]], esp [[levofloxacin]] | *[[Quinolones]], esp [[levofloxacin]] | ||
| Line 16: | Line 17: | ||
*[[Clindamycin]] | *[[Clindamycin]] | ||
*[[Vancomycin]] | *[[Vancomycin]] | ||
==Significant P450 Inhibitors in General== | |||
*Grapefruit juice | |||
*Valproate | |||
*INH | |||
*Protease inhibitors (-navir, i.e. ritonavir) | |||
*SSRIs, except escitalopram | |||
*[[Amiodarone]] | |||
*Fluoroquinolones | |||
*Sulfonamides | |||
*Macrolides | |||
*Cimetidine | |||
*Omeprazole | |||
*Ketoconazole | |||
*Acute EtOH | |||
==Significant P450 Inducers in General== | |||
*Phenytoin | |||
*Carbamazepine | |||
*Ethosuximide | |||
*Quinidine/quinine | |||
*Rifampin | |||
*Griseofulvin | |||
*Glucocorticoids | |||
*Barbituates | |||
*St. John's wort | |||
*Chronic EtOH | |||
*Tobacco smoking | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 17:47, 29 August 2015
Background
Antimicrobials
Avoid / P450 Inhibitors
- Quinolones, esp levofloxacin
- Macrolides, esp erythromycin
- Bactrim and sulfonamides
- Flagyl
- Nafcillin, oxacillin
Use
- Azithromycin
- [[Gentamicin
- Cephalosporin, aminopenicillins
- Nitrofurantoin
- Clindamycin
- Vancomycin
Significant P450 Inhibitors in General
- Grapefruit juice
- Valproate
- INH
- Protease inhibitors (-navir, i.e. ritonavir)
- SSRIs, except escitalopram
- Amiodarone
- Fluoroquinolones
- Sulfonamides
- Macrolides
- Cimetidine
- Omeprazole
- Ketoconazole
- Acute EtOH
Significant P450 Inducers in General
- Phenytoin
- Carbamazepine
- Ethosuximide
- Quinidine/quinine
- Rifampin
- Griseofulvin
- Glucocorticoids
- Barbituates
- St. John's wort
- Chronic EtOH
- Tobacco smoking