Lactulose: Difference between revisions
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**40-90ml/day PO divided TID-QID | **40-90ml/day PO divided TID-QID | ||
**titrate for 2-3 soft stools per day | **titrate for 2-3 soft stools per day | ||
constipation | |||
**1ml/kg PO Qday - BID | |||
**max 60mL/day | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 02:41, 3 September 2015
General
- Type: osmotic laxative
- Dosage Forms: 10g/15L solution
- Routes of Administration: oral, NG, rectal
- Common Trade Names: Kristalose
Adult Dosing
Hepatic encephalopathy
- 30-45mg PO TID or QID or (300mL in 700cc H2O retention enema x30min)
- titrate for 2-3 soft stools per day
constipation
- 15-50mL PO Qday - BID
- max 60mL/day
Pediatric Dosing
portal systemic encephalopathy
- infants
- 2.5-10ml/day PO divided TID-QID
- titrate for 2-3 soft stools per day
- children
- 40-90ml/day PO divided TID-QID
- titrate for 2-3 soft stools per day
constipation
- 1ml/kg PO Qday - BID
- max 60mL/day
Special Populations
- Pregnancy Rating:
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: