Epistaxis: Difference between revisions

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==Treatment ==
==Treatment ==
===Direct Nasal Pressure===
===Direct Nasal Pressure===
#Have pt blow nose to expel clots or suction nose
*Have pt blow nose to expel clots or suction nose
#Instill topical vasoconstrictor (oxymetazoline or phenylephrine)
*Instill topical vasoconstrictor (oxymetazoline or phenylephrine)
#Have pt apply direct pressure over cartilaginous area of nasal bridge (not the bony area)
*Have pt apply direct pressure over cartilaginous area of nasal bridge (not the bony area)
#Pt may lean forward to avoid aspiration of blood
*Pt may lean forward to avoid aspiration of blood


===Chemical Cauterization===
===Chemical Cauterization===
#Consider if two attempts at direct pressure fail
*Consider if two attempts at direct pressure fail
#Only perform if the bleeding vessel is adequately visualized
*Only perform if the bleeding vessel is adequately visualized
#Anesthetize w/ cotton pledgets soaked in 1:1 mix of 0.05% oxymetazoline:4% lidocaine
*Anesthetize w/ cotton pledgets soaked in 1:1 mix of 0.05% oxymetazoline:4% lidocaine
#Once bloodless field obtained, place silver nitrate just proximal to bleeding source
*Once bloodless field obtained, place silver nitrate just proximal to bleeding source
##Leave on for a few seconds at most
**Leave on for a few seconds at most
##Never cauterize both sides of the septum at one go (risk of septal perforation)
**Never cauterize both sides of the septum at one go (risk of septal perforation)


===Thrombogenic Foams===
===Thrombogenic Foams===
#Apply Gelfoam or Surgicel on visualized bleeding mucosa
*Apply Gelfoam or Surgicel on visualized bleeding mucosa
#Bioabsorbable so removal/abx not needed
*Bioabsorbable so removal/abx not needed
===Anterior Nasal Packing===
===Anterior Nasal Packing===
*Only use if all of the above have failed
*Only use if all of the above have failed
#Rapid Rhino
*Rapid Rhino
##Soak balloon w/ water(NOT saline) and insert along the floor of the nasal cavity
**Soak balloon w/ water(NOT saline) and insert along the floor of the nasal cavity
##Inflate slowly with air(NOT saline or water) until the bleeding stops
**Inflate slowly with air(NOT saline or water) until the bleeding stops
#Merocel
*Merocel
##Absorbent nasal tampon
**Absorbent nasal tampon
##Coat tampon w/ water-soluble abx ointment and insert along floor of nasal cavity
**Coat tampon w/ water-soluble abx ointment and insert along floor of nasal cavity
##If tampon has not expanded w/in 30s of placement, irrigate it in place w/ NS
**If tampon has not expanded w/in 30s of placement, irrigate it in place w/ NS
##Moisten three times per day with saline or water until removal
**Moisten three times per day with saline or water until removal
#Traditional Packing
*Traditional Packing
##Apply ribbon gauze in accordion-like manner
**Apply ribbon gauze in accordion-like manner


===Tranexamic acid===
===Tranexamic acid===
#500mg TXA applied to topical foam or non absorbable packing and inserted into nares.<ref>Zahed R. et al. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial.Am J Emerg Med. 2013 Sep;31(9):1389-92</ref>
*500mg TXA applied to topical foam or non absorbable packing and inserted into nares.<ref>Zahed R. et al. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial.Am J Emerg Med. 2013 Sep;31(9):1389-92</ref>
#Can stop bleeding as fast as 10 minutes
*Can stop bleeding as fast as 10 minutes


===Posterior Nasal Packing===
===Posterior Nasal Packing===
#Only consider if all of the above have failed
*Only consider if all of the above have failed
#Associated w/ higher complication rates (pressure necrosis, infection, hypoxia)
*Associated w/ higher complication rates (pressure necrosis, infection, hypoxia)
##Temporizing measure while awaiting ENT support
**Temporizing measure while awaiting ENT support
#Consider nasal block as posterior packing is often very uncomfortable
*Consider nasal block as posterior packing is often very uncomfortable
#All posterior packing should be accompanied by anterior packing
*All posterior packing should be accompanied by anterior packing
#Rapid Rhino
*Rapid Rhino
##Inflate posterior balloon
**Inflate posterior balloon
#Foley catheter w/ 30-cc balloon
*Foley catheter w/ 30-cc balloon
##Lubricate w/ topical antibiotic
**Lubricate w/ topical antibiotic
##Advance transnasally until visualized in posterior oropharynx
**Advance transnasally until visualized in posterior oropharynx
##Inflate balloon w/ 7cc of saline; retract 2-3cm until lodged in post nasopharynx
**Inflate balloon w/ 7cc of saline; retract 2-3cm until lodged in post nasopharynx
##Inflate w/ additional 5-7cc of saline to complete the pack
**Inflate w/ additional 5-7cc of saline to complete the pack
#Keep packing for 72-96 hours, <48 hours associated with increased re-bleed.
*Keep packing for 72-96 hours, <48 hours associated with increased re-bleed.


==Disposition==
==Disposition==

Revision as of 02:31, 5 October 2015

Background

Types

  • Anterior
    • 90% of nosebleeds
    • Occur in anterior septum (Kiesselbach plexus)
    • Can visualize with anterior rhinoscopy
  • Posterior
    • 10% of nosebleeds
    • Occur from nasopalatine branch of sphenopalatine artery
    • Cannot visualize

Risk factors

  • Digital trauma
  • Rhinosinusitis
  • Anticoagulant/antiplatelet use
  • Trauma
  • Neoplasia
  • Hypertension (does not cause bleeding but prolongs existing bleeding)
  • Osler-Weber-Rendu aka hereditary hemorrhagic telangiectasia (HHT)

Clinical Features

Differential Diagnosis

Diagnosis

  • Anterior versus posterior hemorrhage
    • Assume posterior if measures to control anterior bleeding fail
    • Posterior bleeding associated with:
      • Coagulopathy
      • Significant hemorrhage visible in posterior nasopharynx
      • Sensation of blood dripping down throat
      • Hemorrhage from bilateral nares
      • Epistaxis uncontrolled w/ either anterior rhinoscopy or anterior pack

Treatment

Direct Nasal Pressure

  • Have pt blow nose to expel clots or suction nose
  • Instill topical vasoconstrictor (oxymetazoline or phenylephrine)
  • Have pt apply direct pressure over cartilaginous area of nasal bridge (not the bony area)
  • Pt may lean forward to avoid aspiration of blood

Chemical Cauterization

  • Consider if two attempts at direct pressure fail
  • Only perform if the bleeding vessel is adequately visualized
  • Anesthetize w/ cotton pledgets soaked in 1:1 mix of 0.05% oxymetazoline:4% lidocaine
  • Once bloodless field obtained, place silver nitrate just proximal to bleeding source
    • Leave on for a few seconds at most
    • Never cauterize both sides of the septum at one go (risk of septal perforation)

Thrombogenic Foams

  • Apply Gelfoam or Surgicel on visualized bleeding mucosa
  • Bioabsorbable so removal/abx not needed

Anterior Nasal Packing

  • Only use if all of the above have failed
  • Rapid Rhino
    • Soak balloon w/ water(NOT saline) and insert along the floor of the nasal cavity
    • Inflate slowly with air(NOT saline or water) until the bleeding stops
  • Merocel
    • Absorbent nasal tampon
    • Coat tampon w/ water-soluble abx ointment and insert along floor of nasal cavity
    • If tampon has not expanded w/in 30s of placement, irrigate it in place w/ NS
    • Moisten three times per day with saline or water until removal
  • Traditional Packing
    • Apply ribbon gauze in accordion-like manner

Tranexamic acid

  • 500mg TXA applied to topical foam or non absorbable packing and inserted into nares.[1]
  • Can stop bleeding as fast as 10 minutes

Posterior Nasal Packing

  • Only consider if all of the above have failed
  • Associated w/ higher complication rates (pressure necrosis, infection, hypoxia)
    • Temporizing measure while awaiting ENT support
  • Consider nasal block as posterior packing is often very uncomfortable
  • All posterior packing should be accompanied by anterior packing
  • Rapid Rhino
    • Inflate posterior balloon
  • Foley catheter w/ 30-cc balloon
    • Lubricate w/ topical antibiotic
    • Advance transnasally until visualized in posterior oropharynx
    • Inflate balloon w/ 7cc of saline; retract 2-3cm until lodged in post nasopharynx
    • Inflate w/ additional 5-7cc of saline to complete the pack
  • Keep packing for 72-96 hours, <48 hours associated with increased re-bleed.

Disposition

Anterior Epistaxis

  • Discharge after 1hr of observation
  • Pts w/ therapeutic warfarin levels may continue medication
  • Discontinue NSAIDs for 3-4d
  • Possible amoxicillin-clavulanate if anterior packing was placed as prophylaxis for bacterial sinus infection or Toxic shock syndrome although no robust evidence base[2]
  • ENT or ED follow-up in 2-3d for removal of nonbiodegradable packing

Posterior Epistaxis

  • Admission is strongly advised

Complications

References

  1. Zahed R. et al. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial.Am J Emerg Med. 2013 Sep;31(9):1389-92
  2. Cohn B. Are prophylactic antibiotics necessary for anterior nasal packing in epistaxis? Ann Emerg Med. 2015 Jan;65(1):109-11
  3. Primary malignant melanoma of the nose: a rare cause of epistaxis in the elderly. PDF
  4. Kaposiform hemangioendothelioma arising in the ethmoid sinus of an 8‐year‐old girl with severe epistaxis PDF