Template:PCP pneumonia antibiotics: Difference between revisions
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====Mild Disease==== | ====Mild Disease==== | ||
*[[TMP/SMX]] 2 DS tablets PO q8hrs daily OR | *[[TMP/SMX]] 2 DS tablets PO q8hrs daily OR | ||
**High incidence of allergy in HIV | |||
*[[Dapsone]] 100mg PO once daily + [[TMP]] 5mg/kg PO q8hrs OR | *[[Dapsone]] 100mg PO once daily + [[TMP]] 5mg/kg PO q8hrs OR | ||
**''caution: dapsone | **''caution: dapsone can cause methemoglobinemia'' | ||
*[[Atavaquone]] 750mg PO q12hrs OR | *[[Atavaquone]] 750mg PO q12hrs OR | ||
*[[Primaquine]] 30mg PO q24hrs + [[Clindamycin]] 450mg PO q8hrs | *[[Primaquine]] 30mg PO q24hrs + [[Clindamycin]] 450mg PO q8hrs | ||
Latest revision as of 18:28, 22 February 2016
Mild Disease
- TMP/SMX 2 DS tablets PO q8hrs daily OR
- High incidence of allergy in HIV
- Dapsone 100mg PO once daily + TMP 5mg/kg PO q8hrs OR
- caution: dapsone can cause methemoglobinemia
- Atavaquone 750mg PO q12hrs OR
- Primaquine 30mg PO q24hrs + Clindamycin 450mg PO q8hrs
Severe Disease
- TMP/SMX 5mg/kg IV q8hrs daily x 21 days OR
- Pentamidine 4mg/kg IV daily infused over 60 minutes OR
- Watch for side effects of hypoglycemia and hypotension
- Primaquine 30mg PO once daily + Clindamycin 900mg IV q8hrs daily
Prophylaxis
- TMP/SMX 1 double strength tablet daily, but one single strength tablet daily or one double-strength three times weekly is acceptable.[1]
- ↑ CDC Guidelines for Prophylaxis Against Pneumocystis carinii Pneumonia for Children Infected with Human Immunodeficiency Virus http://www.cdc.gov/mmwr/preview/mmwrhtml/00001957.htm