Bath salts toxicity: Difference between revisions

m (moved Synthetic Cannabinoids (Bath Salts) to Bath Salts: Bath salts aren't synthetic cannabinoids)
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== Background ==
== Background ==
*Found in herbal products sold over the internet or convenient stores under guise of bath salts "not for human consumption"
*Found in herbal products sold under guise of "not for human consumption"
**May be found under brand name Aura, Ivory wave, Vanilla sky
**May be found under brand name Aura, Ivory wave, Vanilla sky
*Active ingredients vary widely
*Active ingredients vary; often contain methylenedioxyprovalerone (MDPV) or mephedrone
**Methylenedioxyprovalerone (MDPV)
**Methadrone
*Similar effects to MDMA, cocaine, methamphetamines
*Similar effects to MDMA, cocaine, methamphetamines


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== Treatment ==
== Treatment ==
*Benzodiazepines or Haldoperidol for agitation
*Benzodiazepines or haldol for agitation
*Rapid cooling for hyperthermia
*Rapid cooling for hyperthermia
**cooling blankets
**cooling fans
**Ice packs
*IV hydration
*IV hydration
*Monitor urine output
*Monitor urine output


== Disposition ==
== Disposition ==
*Patients whose altered mental status and sympathomimetic symptoms resolve and do not demonstrate evidence of end organ damage may be discharged
*Discharge if AMS and sympathomimetic symptoms resolve w/o e/o end-organ damage
*Admit patients with laboratory abnormalities or persistent altered mental status
*Admit for lab abnormalities or persistent AMS
 


== Sources ==
== Sources ==
*Uptodate
*UpToDate
*EMRAP
*EMRAP


[[Category: Tox]]
[[Category: Tox]]

Revision as of 03:53, 5 January 2012

Background

  • Found in herbal products sold under guise of "not for human consumption"
    • May be found under brand name Aura, Ivory wave, Vanilla sky
  • Active ingredients vary; often contain methylenedioxyprovalerone (MDPV) or mephedrone
  • Similar effects to MDMA, cocaine, methamphetamines

Clinical features

  • Sympathomimetic toxidrome
    • Tachycardia
    • Hypertension
    • Agitation
    • Paranoia
    • Hyperthermia
  • Hallucinogenic

Diagnosis

  • Diagnosis based on history and physical exam

Work-Up

  • Fingerstick glucose
  • Complete metabolic panel
  • LFTs
  • Coags
  • Total CK
  • Utox not helpful, usually negative

DDX

Treatment

  • Benzodiazepines or haldol for agitation
  • Rapid cooling for hyperthermia
  • IV hydration
  • Monitor urine output

Disposition

  • Discharge if AMS and sympathomimetic symptoms resolve w/o e/o end-organ damage
  • Admit for lab abnormalities or persistent AMS

Sources

  • UpToDate
  • EMRAP